Everyone over the age of 30 harbors parasites, the question is how well you deal with them. They're excellent at remaining undected, though it intuitively feels like I have them (a body mind feeling). As CFS sufferers we have such low energy, it makes sense to kick out anything that would drain us
Skill Level 3
Relevance:4 Technical Level:2
page 72 DRAIN ELIMINATE REBUILD (TISSUES, PATHWAYS) DETOX > PARASITE TESTING and CLEANSE
Test Comprehensive Digestive Stool Analysis with Parasitology - Genova Lab
Sample required stool
This test gives an idea of how well foods are digested and absorbed, gives some products of gut fermentation, looks for blood in the stool, gives counts of bacteria and yeast, identifies those organisms which should not be there and lists antibiotic and/or antifungal preparations, both herbal and drug, to which that micro-organism is sensitive. It also looks for parasitic micro-organisms such as amoeba, blastocystis hominis, cryptosporydia and giardia lamblia and suggests possible treatment options.
The stool analysis is carried out at Genova Diagnostics in the USA
This test is performed on stool samples collected over 3 days and provides a detailed assessment of gut flora. It reports on bacterial and yeast flora, both beneficial and pathogenic as well as looking for parasitic micro-organisms such as amoeba, blastocystis hominis, cryptosporydia and giardia lamblia etc. . It also provides an overview of available treatments and their efficiency for treating bacterial and yeast dysbiosis.
The analysis is carried out at Genova Diagnostics in the USA
Laboratory Genova Diagnostics
Sample required stool sample
This test is performed on stool samples collected over 3 days and looks for and identifies parasitic micro-organisms such as amoeba, blastocystis hominis, cryptosporydia and giardia lamblia etc.
If a more detailed assessment of gut flora is needed, then Comprehensive parasitology might be useful. This test reports on bacterial and yeast flora as well as looking for parasites in the stool samples. It also provides an overview of available treatments for bacterial and yeast dysbiosis.
The analysis is carried out at Genova Diagnostics
test Ova, Cysts and Parasites
Parasitic Examination, Stool https://www.labtestsonline.org.au/learning/test-index/o-and-p-or-ocp
Medical science simply doesn't have good "broad" and reliable parasite testing available unless one is in a research lab. There are some species specific antibody and PCR tests but given the thousands of different parasites, its absurd to think a doctor would guess correctly assuming they were willing to try. The Mayo Clinic ran one antibody test and Stanford ran the same antibody test based on my high IgE and EOS. Of course they were negative and that ended their effort.
When I learned that the company Ubiome was beginning to offer a Metagenomic sequencing based stool test, the "Explore Plus" last year that didn't just cover Bacteria and Archaea via 16S sequencing but also virus's and Eukaryotes, I ordered the 4 test kits for $399. Both Fungi and Parasites are Eukaryotes. Because of their wide variety and genetic breadth, using a marker sequencing via PCR just isn't effective as it is in Bacteria. Metagenomic sequencing has the incredible advantage that it doesn't assume or require guessing about "what infection you have" but simply reports all the organisms DNA it found and then a computer sorts out the "junk". Its far from perfect but it avoids the doctor "guessing" and testing.
So rather than more testing, I began empirically treating it with albendazole and Praziquantel and both can cross the BB barrier. They are quite safe being used in the 100's of millions worldwide due to worm infections being common in the third world. On the third day, my constipation stopped like a miracle after 3 years of struggles. The bodywide pain declined in a near magic way. But the neurological symptoms flared including some new problems. Is it Neurocysticercosis? The Cysts are far more difficult to clear in the brain than elsewhere. The CDC says it requires 14-28 days of the anti-parasitics for Neurocysticercosis due to this difficulty.
So here I am after my first week on albendazole and Praziquantel and the changes are dramatic but the jury is still out. I thought I would share my experience here since I've seen so many people describe their symptoms as seemingly revolving around their diet, sugar and gut and IBS like symptoms. But these also include many non-gut such as fatigue, neurological and pain conditions etc..
Ivermectin 12 mg 3-4x/day with pyrantel pamoate 250 mg 3-4x/day
Praziquantel 600 mg 4x/day or Levamisole 50 mg 4x/day
Tinidazole 500 mg 3 – 4x/day
Alinia (nitrazoxanide) 500 mg 3x/day
Albendazole 400 mg 2x/day
Most Common Fungal Protocols
Diflucan (fluconazole) 200 mg 1x/day
Diflucan (fluconazole) 200 mg 1x/day + Nystatin capsules 500,000IU 4x/day
Diflucan (fluconazole) 100 mg 1x/day + Sporanox (itraconazole) 100 mg 1x/day
Sporanox (itraconazole) 200 mg 1x/day
Ketaconazole 200 mg 2x/day
Ivermectin is an effective anti-parasitic. But it's also virus inhibitory (for COVID-19), blocking certain viral proteins, modulating the immune system, and an anti-inflammatory
So I wanted to get feedback on the parasite angle and alert people that the Ubiome Explorer Plus may be an important tool for looking at whats in their gut besides bacteria. One can see if there are any fungi or parasites that might be at the root of their problems living in their gut. After realizing Medical Science is so poor at finding parasites, I couldn't help but wonder how common long living parasite infections like the various worms are in the CFS/ME population? Love to hear your thoughts plus I'm curious if anyone has had the key markers of high IgE and Eosinophils that seem to be a glaring "hint" doctors just don't realize what it might mean. Humans developed both IgE and Eosinophils as a "worm" defense since early man had serious problems with worms. They have evolved into the "allergy" markers only in recent times. If you know you have high total IgE and odd Eosinophils popping up in CBCs', you should look into this. I'm not a doctor but this is something you should explore with your doctor as it appears to be a glaring hole only rarely discovered due to lack of doctor knowledge and extremely poor testing
buy pyrantel from an online store (such as Amazon). This is the anti-parasitic given to Australian children, it often has instructions for human use, although in the US it's sold as a cat anti-parasitic. In any case, it's safe for human use.
I took it after I cleaned up my cat from a flea and worms infestation. It seemed to also help me feel more energetic, since then I've repeated taking it about three times a year. Every time I feel better for a while. I went to see an infectious disease doctor, it was a disaster, they completely ignored my problems. One of the worst experiences of my life with any doctor.
If your pet goes outside, you must use ivermectin type meds to keep them safe and yourself safe. Only a vet can give your cat that med, at the proper dose, it covers many types of worms although for active tapeworm they may use a different med.
Yes infection can lead to ME/CFS. If you suspect a parasite a visit to a functional MD may be the ticket. Here's one doctor talking about it on her blog: https://www.amymyersmd.com/2017/05/10-signs-you-may-have-a-parasite
Dr. Leo Galland concerning research about CFS and parasites. He is a top tier CFS doctor and his quote was the first thing he looks for in CFS is a parasite infection. He gave up on standard O&P tests since they are unreliable (but different now as you mentioned).
I did a multitude of testing and found a protozoa infection in one of the tests. For those who are unfamiliar with parasites, there are different classes, for instance pgrovetom had a worm (which has a few classifications such as nematode, cestode and trematode) while I had a protozoa infection (think of giardia, cryptosporidium etc). They are both parasites classifications but different in treatment strategies.
Education in the medical community is sorely lacking concerning parasites and testing is the big problem, but they are getting better. One of the laughable excuses I heard and read is that since you live in a developed country (US), therefore you cannot have parasites. This is simply false (think of global travel, imported produce etc). In fact, there was a big breakout in Milwaukee that was labelled as CFS. Turns out that cryptosporidium was found in the water supply.
I wrote a blog article that might be helpful (needs editing, so forgive me for the sloppy post).
Model and actress Yolanda Hadid 'Regular colonics at the Gentle Wellness Center in Santa Monica, Calif., helped Yolanda expel a 16-inch “monster” she suspects had been living in her body for 20 to 30 years. The discovery kicks off an obsession'
page 72 DRAIN ELIMINATE REBUILD (TISSUES, PATHWAYS) DETOX > PARASITE TESTING and CLEANSE
Testing Laboratories, Treatment Centers, Specialists and Clinics
Testing for amount and kind of brain cells by evaluating R2t* signal from MRI scan
Hormone Replacement Therapy (HRT)
Disruption in Blood Brain Barrier and (mast cell or astrocyte) production cytokine