Product, medication,
therapy, latin name,
linklist (Clusty.com)
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Contents, scientific name, foreign name, Wikipedia informationResearch
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/ abstractsDetails
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/ Dose / Links
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Use the "Control" + "F" button on your
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Acclydine
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Acclydine is an alkaloid, derived from selected plants that have
substantial effects on the protein structure and the metabolism.
At cellular it affects the activation of insulin-like growth factor (IGF-1)
receptor.
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...the researchers tested levels
of IGF-1 and IGF-BP-3 in the patient’s blood before Acclydine
was taken...
Value of IGF-BP-3 / IGF-1 General Response to Acclydine:
4.5 or greater : Greatest
Probability of Response
3.5 to 4.5 : Some patients responded, some did not
Less than 3.5 : Most patients did not respond
The researchers concluded that Acclydine is best
suited for patients with a ratio of IGF-BP-3/IGF-1 greater than 3.5. Patients
with a ratio greater than 3.5 have a IGF-1
deficiency.
In the case the ratio is less than 3.5, but the concentration of IGF-1 is
higher than normal, it might be useful to begin with a low dose of Acclydine, 1-2 capsules per day.
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Methods: 90 individuals suffering
from CFS (Holmes and/or Fukuda criteria) entered the study. They were not
allowed to take any other medication than minor pain relievers and
homeopathic medication.
The treatment protocol consisted of first 4 weeks: 250 mg four times a day in
combination with amino acids; second 4 weeks 250 mg Acclydine
twice daily in combination with amino acids. The primary efficacy variable
was the change from baseline in CFS as measured by the Clinician’s Global
Impression Scale (CGI) after 4 and 8 weeks of treatment. Secondary endpoints
were: IGF-1, IGF-BP3 values, LMW/HMW RNase L ratio, GHQ-30, POMS, SF-36 and
SCL-90.
Conclusions:
Acclydine in combination with amino acids gives an
improvement in CFS symptoms (54% in the active group compared to 16% in the
placebo group). No major adverse events were noted. Acclydine
appears to be a safe and adequate drug for CFS.
This study was sponsored by
Optipharma ,The Netherlands.
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Aloe
(diverse)
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Anti inflammatory, anti-viral,
anti fungal, immune enhancer (?)
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In one of the few studies in which possible effects have
actually been measured, fm/cfs-patients
who consumed a nutritional supplement containing freeze-dried aloe vera
extract, which is rich in acetylated mannans, reported significant
improvement in their symptoms.
(Dykman KD ; Ford CR :
A longitudinal study of the effects of dietary supplements on the symptoms of
fm/cfs 1998)
Glycoscience.com
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Amino acids
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Amino Acids (Wikipedia)
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Anti-microbial, stimulates white blood cells (?)
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Interesting info on Amino acids:
Aminoacidpower.com
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Ampligen
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W A R N I N G !
Ampligen is a very controversial drug! There are
opposing views concerning the honesty of the company Hemispherx
and the efficacy of the drug.
Read this before trying Ampligen:
Asensio.com on Hemisperx
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HOWEVER, I found this on
CFSFMExperimental-yahoogroup:
"...and hasn't Asensio & Company been charged
and on several counts fined by the court with manipulating stock and bringing
about the destruction of many companies?
I wouldn't trust them as a source of information, because they have a vested
interest in making money off their accusations, and they've gained a
reputation for unethical behavior..."
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Die Therapie mit
dem Ampligen Poly (1).poly
(C12U) kann zu einer Verbesserung der körperlichen und mentalen Leistungsfähigkeit führen.
(Ebene II)
o uni-züri/klipsy.ch
Ampligen is an investigational drug produced by Hemispherx Biopharma.
It is a modified RNA molecule. Previous double-blind studies in the U.S. and
Europe have had encouraging results. There have not been major side-effects
directly attributable to the drug. The current 516 study is a "phase
III" study, the final step before a drug is considered for approval by
the FDA.
Dr. Podell's Ampligen program
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Andrographis
Andrographis paniculata
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- Diterpene lactones (Andrographolides)
Chinese: Chuan xin lian
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Andrographis is believed to have
immune-stimulating, anti-inflammatory, fertility-decreasing,
liver-protective, and bile secretion-stimulating actions. Though some older
studies suggested andrographis was antibacterial,
modern research has been unable to confirm this finding.
... supposedly most helpful for the URI's (upper respiratory tract
infections) that hit CFS patients. Also, clot busting.
Details on Andrographis can be found at:
Altcancer.com/andcan.htm
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Several double-blind clinical trials have found that andrographis can help reduce symptom severity in people
with common colds. Though the earliest clinical trial among these showed
modest benefits, later studies have tended to be more supportive.
Standardized andrographis extract combined with
eleuthero (Siberian ginseng), known as
Kan jang, has also been shown in a double-blind
clinical trial to reduce symptoms of the common cold.
A preliminary uncontrolled study
using isolated andrographolide found that while it tended to decrease viral
load and increase CD4 lymphocyte levels in people with HIV infection, at the
amount used, the preparation led to side effects, including headache,
fatigue, a bitter/metallic taste in the mouth, and elevated liver enzymes
(which returned to normal after the medication was stopped). It is unknown
whether the andrographolides used in this study directly killed HIV or had an
immune-strengthening effect.
Healthwell.com/andrographis
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Antioxidants
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Antioxidant (Wikipedia)
In addition to enzymes, many vitamins and minerals act as antioxidants in
their own right, such as:
- vitamin C
- vitamin E
- beta-carotene
- lutein
- lycopene
- vitamin B2
- coenzyme Q10
- cysteine (an amino acid).
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Herbs, such as:
- bilberry
- turmeric (curcumin)
- grape seed
- pine bark extracts
- ginkgo
can also provide powerful anti-oxidant protection for the body.
Free radicals are highly reactive compounds that are created in the body
during normal metabolic functions or introduced from the environment. Free
radicals are inherently unstable, since they contain “extra” energy.
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To reduce their energy load, free radicals react with
certain chemicals in the body, and in the process, interfere with the cells’
ability to function normally.
In fact, free radicals are believed to play a role in more than sixty
different health conditions, including the aging process, cancer, and
atherosclerosis.
Reducing exposure to free radicals and increasing intake of antioxidant
nutrients has the potential to reduce the risk of free radical-related health
problems.
Healthwell.com/antioxidants
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Ashwagandha
Withania somnifera
(Indian ginseng)
(Winter cherry)
(Ajagandha)
(Kanaje Hindi)
(Samm Al Ferakh)
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"...The species name somnifera means "sleep-bearing" in Latin,
indicating it was considered a sedative, but it has been also used for sexual
vitalityand as an adaptogen.
Some herbalists refer to ashwagandha as Indian ginseng, since it is used in
ayurvedic medicine in a way similar to that ginseng is used in traditional
Chinese medicine..."
Ashwagandha (Wikipedia)
"Withania is used to treat debility, and nervous
exhaustion. It is also good for increasing body weight especially
for very thin emaciated children. It is a nervine sedative, anti-inflammatory, tonic and adaptogen. It boosts
the immune system and is a calming stress reliever"
Chrysalis4me.com/herbpage
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"...Generally,
ashwagandha stimulates the immune system. It has also been shown to inhibit
inflammation and improve memory.
Taken together, these actions support the traditional reputation of
ashwagandha as a tonic or adaptogen. It
counteracts the effects of stress and generally promote wellness..."
Holistic-online.com/ashwagandha
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"...Ashwagandha root, is an
important herb from the Ayurvedic or Indian system of medicine. Ashwagandha
has been traditionally used for the treatment of debility, emaciation, impotence,
and premature aging. This dietary supplement is used to enhance
mental and physical performance, improve learning ability,
and decrease stress and fatigue.
Ashwagandha is a general tonic to be used in stressful situations,
especially insomnia, overwork, nervousness,restlessness, and CFS..."
Immunesupport.com/articles
Boone K. Withania 1998
The Indian Ginseng and Anti-aging Adaptogen. Nutrition and Healing.
Singh A, Naidu PS, Gupta S, Kulkarni. 2002 Effect of natural and
synthetic antioxidants in a mouse model of chronic fatigue syndrome. J Med
Food.
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Astragalus
Astragalus membranaceous
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Chinese: Huang qi
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Supports T-cells, adrenals, anti-toxin (?)
Astragalus has been valued by the Chinese for centuries for its
immune-enhancing and adaptogenic properties. As an
adaptogen, it may modify and improve the body’s response to stress through
action on the adrenal cortex.
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Chang CY, et al. 1983
Effects of Astragalus membranaceus on Enhancement
of Mouse Natural Killer Cell Activity.
Zhao KS, et al. 1990
Positive Modulating Action of Shengmaisan with
Astragalus membranaceus on Anti-tumor Activity of
LAK Cells.
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Azithromycin
(Zithromax)
(Zmax)
(Sumamed)
(Aztrin)
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Azithromycin is an azalide, a subclass of macrolide
antibiotics. Azithromycin is one of the world's best-selling antibiotics, and
is derived from erythromycin;
Azithromycin is used to treat certain bacterial infections, most
often bacteria causing middle ear infections, tonsillitis, throat
infections, laryngitis, bronchitis, pneumonia and sinusitis.
It is also effective against certain sexually transmitted infectious
diseases, such as non-gonococcal urethritis and cervicitis.
Azithromycin (Wikipedia)
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"...One doctor gave me
azithromycin for a sinus infection.
It did not help my sinus problems at all, but suddenly my stomach problems
were much better.
I have since learned that azithromycin is one of the antibiotics used to
treat mycoplasmas.
I had not yet heard of mycoplasmas, but it is now apparent that I may have
had an infection..."
Cfs-recovery.org/mycoplasma
"The temporary initial
benefits come crumbling down after not so long, probably because antibiotics
don't address more key upstream issues in ME/CFS."
CFSFMExperimental-yahoogroup/message
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Azithromycin Therapy May Be
Beneficial for Subset of CFS Patients
In a group of 99 Chronic Fatigue Syndrome patients treated experimentally
for six weeks with azithromycin, a subgroup of 58 patients reported a
positive decrease in overall symptom severity. Azithromycin is an antibiotic,
but is also believed to possess beneficial immunomodulation (immune
system affecting) abilities.
...After the azithromycin treatment, the responders’ blood plasma levels
of acetylcarnitine were
lower on average than for the nonresponders.
The researchers speculate that the reason for the lower acetylcarnitine
levels in the responders’ blood has to do with cellular energy production. Acetylcarnitine is involved in the cells’ normal use of
fatty acids to produce energy (oxidation). They cite studies offering
preliminary evidence of a relationship between CFS patients’ fatigue
and dysfunction of cellular energy production, indicating “a complex response
involving acetylcarnitine.”
Are the responders’ cells using more acetylcarnitine,
for example?
Immunesupport.com/azithromycin
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Baclofen
(Kemstro)
(Lioresal)
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Baclofen (brand names Kemstro®
and Lioresal®) is a derivative of
gamma-aminobutyric acid.
It is used for the treatment of spastic movement, especially in
instances of spinal cord injury and in multiple
sclerosis. Its beneficial effects result from actions at spinal and
supraspinal sites. Baclofen can also be used to treat hiccups.
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Historically Baclofen was designed to be a drug for
epilepsy in the 1920’s, and was derived from GABA. The effect on epilepsy was
disappointing but it was found that in certain patients
spasticity decreased.
Baclofen was and is still given orally with variable effects. In the severely
affected children, the oral dose is so high that side effects appear and the
treatment loses its benefit. How and when Baclofen came to be used in the
spinal sack is not really clear but this is now an established method for the
treatment of spasticity in many conditions.
Baclofen (Wikipedia)
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Recommendation by Dr.
Jacob Teitelbaum:
Baclofen: 10 to 20mg 1 to 3 times a day (sedating).
Immunesupport.com/Dr. Jacob
Teitelbaum
(Treatment Protocol for Chronic Fatigue Syndrome & Fibromyalgia)
Dr. Jay Goldstein's treatment
protocol from the book "Betrayal by the Brain":
Ncf-net.org/forum/jay.htm
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Bentonite clay
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Binds the bacterial toxins (?)
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Beta glucan
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Increases blood cell production in bone marrow (?)
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Brewers yeast
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Binds toxins, alters intestinal flora (?)
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Bromelain
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Bromelain (Wikipedia)
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May interfere with the release of toxins (?)
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Bromocryptine
(Parlodel)
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Bupropion
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MAO- Hemmer
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Ebenfalls eine Verbesserung
psychischer Variablen bewirken Bupropion (Ebene III-3) und Nefazodon
(Ebene III-3).
uni-züri/klipsy.ch
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Burdock root
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Fights staph
Eliminates toxins (?)
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Butyrate
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Antimicrobial,
increases alkalinity (?)
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from a discussion forum:
"I have a high white blood count in my intestines and low butyrate.
Butyrate is a small chain fatty acid that provides fuel for the cells
that line the colon. Psyllium seeds are a soluble fiber that
can raise butyrate.
(Many foods such as oats are soluble fibers too but I'm allergic to them and
they feed the yeast.)"
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Carnitine
(L-Carnitine)
(Acetyl-L-carnitine)
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Carnitine, also known as L-carnitine is an amino acid
responsible for transport of fatty acids into a cell's mitochondria. It is often
sold as a nutritional supplement.
Like all other proteinogenic amino
acids natural carnitine is the L-stereoisomer. It can be synthesised
within the body from the amino acids lysine or methionine.
Vitamin C (ascorbic acid) is essential to the synthesis of
carnitine. It has been speculated that during growth or pregnancy the
requirement of carnitine could exceed its natural production.
Carnitine (Wikipedia)
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Acetyl-L-carnitine or ALCAR, is an acetylated form of
L-carnitine. ALCAR is far superior to normal L-carnitine in terms of
bioavailability in that it is absorbed by the gastrointestinal
tract, enters cells and crosses the blood-brain barrier more readily than
unacetylated carnitine.
ALCAR has a broad range of uses including combination with alpha lipoic acid
to comprise a patented formulation that has been evidenced to
"rejuvenate" the mitochondria of aging mice in studies conducted by
Bruce Ames and others. Accordingly, acetyl-L-carnitine has potential as a
life extension supplement probably capable of improving the quality and possibily also extending the average life-span of humans.
Other attributed uses for ALCAR include using it as a treatment for
depression (250 mg per day for several weeks) and for clearing plaque/fatty
deposits out of the veins and arteries.
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Some researchers suggest that
L-carnitine and coenzyme Q10 might have an additive or
synergistic effect.
Both coenzyme Q10 and L-carnitine are involved with maintaining
mitochondrial energy production in cells and may help protect against
oxidative and toxin-induced damage.
Naturaldatabase.com
Dose: 3 x 1g daily.
L-Carnitin bewirkt eine Verbesserung in somatischen und die Lebensqualität
betreffenden Variablen
(Ebene III-4), sowie physiologischen
Variablen (Ebene III-3).
uni-züri/klipsy.ch
“L-Carnitine was found to promote statistically significant clinical
improvement in 12 of 18 CFS patients. Along with helping to reduce physical
fatigue, our study showed that L-Carnitine also helped aspects related to
mood as well as mental fatigue. L-Carnitine is a very safe and well-tolerated
naturally occurring amino acid which improves the clinical status of CFIDS
patients.” - Dr. Audrius V. Plioplys, M.D., Chronic Fatigue Syndrome Center and
Department of Research at Mercy Hospital and Medical Center Chicago Illinois.
Rudd Vermeulen (Amsterdam, Netherlands) had
treated 150 CFS patients with oral L-carnitine 1gm bid for 6 months.
69% reported improvement in symptoms.
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Cat's Claw
Uncaria tomentosa
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- Alkaloids
- Sterols
- Glycosides
- Procyanidins and other plant factors
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- antioxidant
- immune stimulating
- antiinflammatory
- cell rejuvenation (?)
- age retarding, reversing (?)
- repairs DNA (?)
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Made from the inner bark of the root, this supplement is
several times stronger than supplements made from just inner bark. Act as a
tonic.
Enhances the immune system's ability to fight viruses, bacteria, intestinal
parasites, and is reported to have anticancer properties.
Dose : 2g per day up to 6g per day
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Chlorella
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Chlorella is more than 50%
protein, 1.6% chlorophyll, and rich in carotenoids, RNA-DNA, B12 and magnesium.
Very similar in nutrients to spirulina &
blue-green algae.
Beyondacenturyonline.com
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Heavy metal and toxin chelator, builds white blood cells,
improves brain function (?)
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Cipro
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cipro.de * bayer.de
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Coconut oil
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Contains monolaurin and Acetyl-l-carnitine (?)
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To disturb the envelope of (?) HHV6 : take 24g (3 tsp.) a day
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Coconut oil links
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Colloidal silver
|
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Alternative to antibiotics. (?)
Some brands work supposedly
against staph, others don't.
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Homecure (Reportedly
the best)
Silver-colloids.com
Utopiasilver.com
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Cordyceps
Cordyceps sinensis
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Cordyceps sinensis is a fungus parasite that lives on
caterpillars in high mountain regions of China.
For commercial purposes, the cordyceps cells (Cs-4 strain) can be
artificially propagated in the laboratory.
Jinshuibao capsules are the commercially available
form of fermented Cordyceps sinensis Cs-4.
other names:
- Caterpillar Fungus
- Cs-4
- Dong Chong Xia Cao
- Dong Chong Zia Cao
- Hsia Ts'Ao Tung Ch'Ung
- Vegetable Caterpillar.
contains:
- Cordyceptic acid
- Adenosine
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This exotic, chinese mushroom is
noted for:
- increases T-cells & NK-cells
- lowers serum lipids (cholesterol)
- raises SOD (antioxidant) levels
- improve kidney function
- increases energy by elevating cAMP & ATP levels
- reducing asthma and respiratory problems,
- lowering blood pressure,
- increasing blood supply to the brain (improving memory and mental
sharpness)
- enhancing sexual vigor.
Has beneficial effects on the immune, endocrine, cardiovascular, respiratory,
renal, sexual, hepatic, immunologic, and nervous systems. Preliminary studies
suggest cordyceps might stimulate immune function by increasing the number of
T helper cells; increasing the natural killer cell activity
; stimulating the blood mononuclear cells ; increasing the levels of
interferon-gamma, tumor necrosis factor-alpha, and interleukin-1; and
prolonging the survival of lymphocytes.
Studies in animals with cancer suggest cordyceps improves immune response,
reduces tumor size and lengthens survival time .
Some evidence suggests cordyceps might be cytotoxic to cancer cells,
particularly lung carcinoma and melanoma. Other evidence suggests that
cordyceps might reduce the risk of renal toxicity from cyclosporine or
aminoglycoside drugs, and prove beneficial in chronic renal failure.
Cordyceps shows evidence that it can inhibit platelet aggregation and
thrombus formation. Other information suggests it might counteract or prevent
arrhythmias, while decreasing heart rate and contractility.
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Cordyceps polysaccharides show evidence that they might
increase corticosterone production. Other studies suggest they might reduce
blood glucose without reducing plasma insulin levels, as well as reduce
plasma triglycerides and cholesterol.
Preliminary animal studies suggest cordyceps could possibly be beneficial in
treating systemic lupus erythematosus. Limited human evidence suggests C. can
improve liver function in patients with chronic hepatitis B.
(Abstracts by: Naturaldatabase.com)
Dose: 1 to 3 grams per day.
---------------------------------------------------
Researchers at Pharmanex in California, which produces a remedy called CordyMax, tried it out on 131 volunteers.
Some were given the remedy and
some a placebo over a 12-week period.
Researchers measured exercise capacity, endurance performance and metabolic
alterations before, during and after receiving the remedy or placebo.
Oxygen
Volume of oxygen consumption went up 5.5% in the group given the remedy, but
only 2.2% in the others, suggesting an increase in aerobic capacity.
The time taken to complete a one-mile walk was reduced by 29 seconds in the CordyMax group but increased slightly in the others. And
diastolic blood pressure fell by 3.2% among people taking the remedy.
The researchers said: "This study provides scientific evidence that CordyMax is effective in enhancing aerobic exercise
capability, endurance exercise performance, and exercise metabolism and
alleviating fatigue in healthy humans."
Bbc.co.uk
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Diazepam
(Valium)
(Stesolid)
(Diazemuls)
(Seduxen)
(Bosaurin)
(Diapam)
(Antenex)
(Apozepam)
|
Diazepam, marketed under brand names Valium, Stesolid, Diazemuls, Seduxen, Bosaurin, Diapam, Antenex and Apozepam is a drug which is a benzodiazepine derivative.
It possesses anxiolytic, anticonvulsant, sedative, skeletal
muscle relaxantand amnestic properties.
This makes it a useful drug for treating anxiety, insomnia, seizures,
alcohol withdrawal, and muscle spasms.
It is also used before certain medical procedures (such as endoscopies) to
reduce tension and anxiety, and in some surgical procedures to induce
amnesia.
Diazepam is a core medicine in the
World Health Organization's "Essential Drugs List", which is a list
of minimum medical needs for a basic health care system. Diazepam is used to
treat a wide range of conditions and is one of the most frequently prescribed
benzodiazepines.
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Over the years, physicians, psychiatrists and neurologists
have discovered many new off-label uses for diazepam, such as treatment
of spastic paresis and palliative treatment of stiff-person
syndrome.
Diazepam is also found in nature. Several plants, such as potato and wheat,
contain trace amounts of naturally occurring diazepam and other
benzodiazepines.
Diazepam (Wikipedia)
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DHEA
Dehydroepiandrosterone
|
DHEA (dehydroepiandrosterone) is a hormone secreted from
the adrenal glands.
It is a precursor of the sex hormones (estrogen and testosterone). DHEA-S has
recently been shown to have beneficial effects on memory, stress, anxiety,
sleep and depression. Therefore, the deficiency of DHEA-S might be related to
the symptoms in patients with CFS.
(van Rensburg, Potocnik et al. 2001)
DHEA has been reported to improve
energy levels in cfs patients.
(Kuratsune, Yamaguti
et al. 1998b)
DHEA has been shown to improve neurological function (including memory, mood
enhancement, and EEG readings), immune surveillance, and stress
disorders.
DHEA is definitely a brain chemical. It's not only utilized by the brain,
it's manufactured
by it.
Although researchers don't know what it's supposed to do yet, they do know
that giving a person 500 mg of DHEA will cause them to have more REM (dream)
sleep.
This indicates a major role in brain chemistry.
|
Treatment with DHEA or Melatoninalone,
as well as together , prevented the reduction of B-
and T-cell proliferation as well as of Th1 cytokine
secretion caused by retrovirus infection. Supplementation also suppressed the
elevated production of Th2 cytokines stimulated by retrovirus
infection.
(Zhang, Araghi-Niknam et al. 1999)
One study showed the value of DHEA and vitamin C infusion
treatment in the control of cfs.
Refer to the
DHEA Replacement Therapy protocolbefore embarking on this therapy.
DHEA replacement therapy has become popular as an antiaging regimen and
offers aging patients help in preventing diseases such as osteoporosis,
fatigue, depression, atherosclerosis, and cancer.
DHEA (50 or 100 mg a day) was also shown to significantly elevate insulin
growth factor (IGF). Aging causes a decline in IGF levels that contributes to
the loss of lean body mass, as well as to excess fat accumulation,
neurological impairment, and age-associated immune dysfunction.
|
One study showed the value of DHEA
and
Vitamin
C infusion treatment in the control of cfs.
(Kodama, Kodama et al. 1996)
A study of 15 subjects with CFS, 15 subjects with major depression, and 11
healthy subjects found that DHEA and DHEA-S levels were significantly lower
in the cfs compared to the healthy group. DHEA-S
levels, but not DHEA, were lower in the depressives. The authors concluded
that DHEA has a potential role both therapeutically and as a
diagnostic tool, in CFS.
(Scott, Salahuddin et al. 1999)
Another study of DHEA levels in 22 CFS patients and 14 healthy controls found
normal basal DHEA levels, but a blunted serum DHEA response curve to ACTH
(adreno-corticotropic hormone) injection.
ACTH normally stimulates the adrenal
glands to secrete DHEA. The authors concluded that endocrine abnormalities
play a role in CFS and that a relative glucocorticoid deficiency might
contribute to the overall clinical picture in CFS. (De Becker, De Meirleir et al. 1999)
Use DHEA up to 4 months for full effect (?)
Remedyfind.com on DHEA
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DMAE
Dimethyl amino-ethanol
|
precursor to Choline and Acetylcholine
|
- stimulant
- improves daytime energy, attentiveness & concentration.
- sounder, but less sleep
- improves mood
|
Keeps the brain fog at bay and helps with
concentration (?)
DMAE-H3 (Twinlabs- $8.95 a bottle)
You can buy a bottle of DMAE at almost any health food store and try it and
you should know within a week if it helps.
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Doxycycline
|
|
Antibiotic,
against Lyme-Borreliose (?)
|
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Echinacea
Echinacea purpurea
|
|
Fights staph
Immune system stimulant for people suffering from seasonal illness. Use with
care when frequently sick.
|
Science suggests that this herb stimulates macrophage
production.
Die Extrakte der Echinacea purpurea und Panax
ginsengerhöhen bei
CFS- Patienten die Funktion
der natürlichen Killerzellen
(Ebene III-3) und die antikörperabhängige zelluläre Zytotoxizität ADCC
(Ebene III-3).
Universität Zürich / Dr. Jens Gaab
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EDTA
|
|
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EDTA is good at breaking down the calcium shell around the
cells
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Elderberry
|
Black elderberry extract
(Sambucol?)
- Anthocyanin
- Catechin polyphenols
|
- inhibiting flu virus
- reduces oxidation of LDL cholesterol
|
Adaptogen (helps in stress situations). Supposedly an
antioxidant more powerful than blueberry.
Iherb.com
|
Enzymes, digestive
|
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Helps body fight bacteria and absorb nutrients (?)
|
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Essential fatty acid
Omega 3: Alpha-linolenic acid
Omega 6: Linoleic acid
Omega 9: Oil acid
(not essential ?)
|
Flaxseed oil contains linolenic,
linoleic, and oleic acids.
It is among the best sources of alpha-linolenic acid. Linoleic acid and
alpha-linolenic acid are required for the structural integrity of all cell
membranes.
Alpha-linolenic acid raises serum omega-3 polyunsaturated fatty acids,
including eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA).
There is some evidence that flaxseed oil can lower triglyceride levels.
Flaxseed oil seems to have other potentially beneficial cardiovascular
effects.
There is also some preliminary evidence that a low fat
diet plus the flaxseed oil can increase systemic arterial elasticity, which
might improve circulatory function.
Some researchers think flaxseed oil can also decrease platelet aggregation,
and increase the bleeding time, but data are conflicting. Higher serum levels
of linoleic acid, an omega-6 fatty acid contained in flaxseed oil, seems to
protect against ischemic stroke and lacunar infarction, possibly by lowering
blood pressure and improving blood flow by reducing platelet aggregation and
enhancing erythrocyte deformability.
Flaxseed oil is used for rheumatoid arthritis because it might have anti-inflammatory
effects. Alpha-linolenic acid contained in flaxseed oil is a precursor
of
- eicosapentaenoic acid (EPA) and
- docosahexaenoic acid (DHA)
which are converted to non- or anti-inflammatory prostaglandins and
leukotrienes in the body.
Supplementation with flaxseed oil or alpha-linolenic acid increases the ratio
of EPA and DHA to the pro-inflammatory arachidonic acid.
Alpha-linolenic acid has also been reported to suppress the production of
interleukin-1 (IL-1), tumor necrosis factor (TNF), leukotriene B4, and oxygen
free radicals by polymorphonuclear (PMN) leukocytes and monocytes.
There is some evidence that alpha-linolenic acid from flaxseed oil might have
anti-tumor effects, possibly by increasing peroxidation of fatty acids in
tumor cell membranes, or by altering the balance of prostaglandin production
away from tumor promoting prostaglandins of the E2 series. Flaxseed oil seems
to reduce the volume of chemically-induced mammary tumors in animal models.
|
Alpha-linolenic acid is possibly effective:
...when used orally as a part of the diet for the primary prevention of
coronary heart disease. There is some evidence that high dietary intake of
alpha-linolenic acid over a period of 6 years can reduce the risk of
myocardial infarction by as much as 59% in both men and women.
In women, a high dietary intake of alpha-linolenic acid over 10 years can
reduce the risk of fatal ischemic heart disease by 65% ;
however, it is not known if alpha-linolenic acid supplements have these same
benefits.
...when used orally as a part of the diet for secondary prevention of
coronary heart disease.
Starting a Mediterranean diet rich in alpha-linolenic acid and low in
saturated fat and cholesterol after an initial myocardial infarction can
significantly reduce the rate of occurrence of a second myocardial infarction
and death rate.
Over a 27 month period, patients using this diet
seem to be 73% less likely to have a second myocardial infarction and 70%
less likely to die from any cause, compared to the standard postinfarction
diet.
Abstracts from:
Naturaldatabase.com
Another EFA-product:
Efamol marine,
combination of fish oil and evening primrose oil.
(...provides the body with Omega-3 and Omega-6 polyunsaturated fatty acids,
GLA, EPA and DHA. These essential fatty acids enable the body to produce
prostaglandins that help in cell functions, growth and other biological
functions. )
EFA's bewirken in der Anwendung
bei CFS-Patienten eine Verbesserung des
Symptombildes. (Ebene II)
Universität Zürich /
Dr. Jens Gaab
|
Udo's choice oil blend offers Omega-3, 6, 9-acids in a 2:1:1 relation.
Inventor: Udo Erasmus
His book: "Fats that heal, fats that
kill"
Distributor USA: Florahealth.com
Distributor Switzerland: Chrisana.ch
Udo's choice oil blend contains:
• Flax oil
• Sunflower oil
• Sesame oil
• Medium chain triglycerides
• Evening primrose oil (12.6 mg GLA per tablespoon)
• Rice germ & Bran oil
• Soy lecithin
• D-alpha tocopheral (natural Vitamin E)
• Oat germ & Bran oil.
One tablespoon liquid form contains:
• Calories 135
• Total fat 14.5 g
• Saturated fat 1.5 g
• Polyunsaturated fat: (Omega-3 fatty acids 6.4 g, Omega-6 fatty acids 3.2
g)
• Monounsaturated fat (Omega-9 fatty acids 3 g)
• Medium chain triglycerides 231 mg.
Udo's Choice® Ultimate Oil Blend does not contain preformed EPA and DHA as it
is an all vegetarian product. EPA and DHA can
only be obtained preformed in the form of fish oil. As we completely want to
avoid the potential problems of contamination with persistent organic
pollutants, such as dioxins, furans and PCBs, we only use seed oils in Udo's
Choice® Ultimate Oil Blend. The particular combination we used provides the
following "important" fatty acids:
1. Alpha-linolenic acid (ALA), 18:C3-n3, which is the parent of
the omega-3 fatty acid series. If provided in sufficient amounts, ALA is
converted into EPA and DHA. Furthermore, ALA has a host of beneficial
biological effects on its own that are independent of conversion into EPA and
DHA. To facilitate optimal conversion, it is necessary to provide all the
cofactors used by the enzymes involved in the desaturation and elongation of
essential fatty acids (EFAs). The main ones are zinc, magnesium, vitamin B3
(as niacin), vitamin B5, vitamin B6, selenium and vitamin E (preferably as
natural mixed tocopherols). Also, the diet should contain sufficient amounts
of protein (at least 20%E), have a low-glycemic index, have a high ratio of
EFAs to saturated fats and an overall ratio of omega-6:omega-3
of no more than 4:1.
2. Linoleic acid (LA), 18:C2-n6, which is the parent of the
omega-6 fatty acid series that includes gamma-linolenic acid (GLA),
di-homo-gamma-linolenic acid (DGLA) and arachidonic acid (AA). If enough LA
is provided, then the body can convert it into GLA and DGLA. The same issues
as those for ALA also pertain to LA in terms of optimal conversion.
3. GLA, 18:C3-n6, in small amounts.
4. Lauric acid, 12:C0, which is known to stimulate the immune
system and suspected of having an effect on certain groups of vira because it disrupts their lipid envelope.
If people get the recommended dosage of the oil blend, approx. one 15-ml
tablespoon per 25 kg bodyweight daily and make sure they create the right
environment in their body to facilitate optimal conversion (as mentioned
above), then ample amounts of EPA, DHA and GLA should be produced in the body.
|
Feverfew
Tanacetum parthenium
|
|
Feverfew has been used for reducing fever, for
treating headaches and for arthritis. Modern
work has supported the use of feverfew as a treatment for migraine
headaches.
Feverfew (Wikipedia)
|
Feverfew has been tried with reports of success for Epstein-Barr
virus (EBV), but no formal studies have been done.
Lassesen.com/cfids/ebv.htm
|
Flavonoids
|
Flavonols: Quercetin,
Kaempferol, Myricetin, Isorhamnetin
Flavones: Luteolin, Apigenin
Flavanones: Hesperetin, Naringenin, Eriodictyol
Flavan-3-ols: (+)-Catechin, (+)-Gallocatechin,
(-)-Epicatechin, (-)-*Epigallocatechin, (-)-Epicatechin 3-gallate,
(-)-Epigallocatechin 3-gallate, Theaflavin, Theaflavin 3-gallate, Theaflavin
3'-gallate, Theaflavin 3,3' digallate, Thearubigins
Isoflavones: Genistein, Daidzein, Glycitein
Anthocyanidins: Cyanidin, Delphinidin, Malvidin, Pelargonidin,
Peonidin, Petunidin
|
Flavonoids are a large group of low molecular weight
polyphenolic phytochemicals found in all vascular plants.
In the diet, flavonoids are found in many fruits, vegetables, and processed
plant-derived foods such as teas and wines.
The beneficial effects of fruits and vegetables are often attributed to
flavonoid compounds rather than known nutrients as they show a wide range of
biological effects including anti-inflammatory, anti-allergic, and
anti-cancer activity.
|
Cocoa,
particularly dark chocolate, is loaded with the flavonoid epicatechin and
has been found to have nearly twice the antioxidants of red wine and up to
three times those found in green tea. Epicatechin improves blood flow and
thus are good for cardiac health.
Good sources of flavonoids include citrus fruits, berries,onions, parsley, legumes, green
tea, red wine, and dark chocolate with a
cocoa content of 70% or greater.
Flavonoids (Wikipedia)
|
Gabapentin
(Neurontin)
|
Neurontin, Parke-Davis’ brand name for gabapentin, is a
unique anticonvulsant, chemically unlike any other drugs available to treat
seizures. It was approved in 1993 for the treatment of seizure disorders
after extensive testing with epilepsy patients. Ever since, clinicians and
researchers have been experimenting with and studying neurontin
for a growing assortment of conditions, particularly mood disorders and
neuropathic pain (pain associated with a nervous system injury or
disease).
---------------------------------------
---------------------------------------
from: Dr. Charles Shepherd
A new drug treatment for moderate to severe nausea/feelings of sickness (?)
A small minority of people with ME/CFS, often the more severely
affected, experience quite severe problems with nausea. And it can be
a very difficult symptom to relieve.
Gabapentin (trade name = Neurontin) is an anticonvulsant drug that is
increasingly being used for the relief of moderate to severe neurological
pain.
I know that quite a few people with ME/CFS have gained benefit from
gabapentin, and it's a drug that I sometimes recommend or prescribe myself.
|
With ME/CFS patients, gabapentin can be effective at very
low doses and most people don't experience any major problems with
side-effects.
Today's edition of the Lancet
(ref: May 17, 361, 1703-1705) carries an interesting short report on the
'effect of gabapentin on nausea induced by chemotherapy in patients with
breast cancer'. 6/9 patients reported a significant improvement and 3/9 had a
complete resolution of their nausea. The authors, from Rochester USA, go on
to describe how gabapentin may be relieving nausea by its effect on
sickness-producing brain chemicals called tachykinins. They also refer to the
fact (which I wasn't aware of) that gabapentin can reduce hot flushes
This is an interesting small study and I would be interested to hear
from anyone with ME/CFS who has been prescribed gabapentin for pain relief
(and has nausea as well) as to whether it had any effect on their feelings of
sickness. Also, has anyone been prescribed gabapentin for nausea related to
ME/CFS?
Dr Charles Shepherd (UK)
|
Dr. Goldstein recommendation
---------------------------------------------
Dr. Jay Seastrunk:
Parke-Davis, the company that purchased gabapentin, has seen dosages
that range from 3,000 to 6,000 mg per day while, even at 10,000, the drug is
not toxic.
Dr. Seastrunk has never found anyone to be
allergic to Neurontin in the hundreds of patients he has treated.
It does not cross-react with other medications. Magnesium, however, will
block Neurontin.
Ncf-net.org (The National Forum)
Brain injury in cfids and mcs
Researchers explore many uses for Neurontin (Cfids.org)
---------------------------------------------
Dr. Paul Cheney:
...believes Neurontin can help "protect the brain" from further
damage He has said that an injured brain may respond to lesser stimuli than a
healthy brain, and this overstimulation of the brain may contribute to
feelings of fatigue and pain. He has found that Neurontin seems to raise the
sensitivity threshold of the brain’s pain response in CFIDS patients.
...Neuroprotection - The brain is injured in a monotonous way. It fires at
lower threshold levels. Therefore, information density will confuse,
sensitivity to light, pain intensified, cannot sleep, hearing is amplified. Drugs
which treat this are magnesium, klonopin, neurontin, doxapin, nicotine,
and narcotics. These need to be titrated at small optimum doses
different for each patient. These drug perserve the
brain from damage.
Lecture by Dr. Cheney, May 7, 1998
--------------------------------------------
Gabapentin (Wikipedia)
|
Garlic
Allium sativum
|
Garlic is a bulbous perennial food plant of the family
Alliaceae
Components; Phytochemicals:
Allicin
Beta-carotene
Beta-sitosterol
Caffeic acid
Chlorogenic acid
Diallyl-disulfide
Ferulic acid
Geraniol
Kaempferol
Linalool
Oleanolic acid
P-coumaric acid
Phloroglucinol
Phytic acid
Quercetin
Rutin
S-allyl cysteine
Saponin
Sinapic acid
Stigmasterol
|
Components; Nutrients:
Calcium
Folate
Iron
Magnesium
Manganese
Phosphorus
Potassium
Selenium
Zinc
Vitamin B1 (Thiamine)
Vitamin B2 (Riboflavin)
Vitamin B3 (Niacin)
Vitamin C
|
Anti-microbial, anti-yeast, anti-fungal.
Inhibits bacteria by disrupting their enzyme function
Natural Yeast Treatments:
Fresh Garlic, if you can handle it well, can also be very effective.
Daily, crush 1 to 3 garlic cloves in olive oil, add salt, spread it on bread
and eat it. It can be quite tasty and lethal to whatever infections you have
in your gut.
Immed.org/teitelbaum
|
Ginger
Zingiber officinale
|
- Gingerols
Ginger (Wikipedia)
|
Fights nausea/dizziness very effectively - see my longterm success in
fighting nausea and dizziness with ginger!
- antioxidant
- thermogenic
- lowers cholesterol
- increases glutathione levels
- protects the liver
- improves digestion & appetite
|
Also supposed to inhibit abnormal blood platelet
aggregation while increasing ATP and 'calcium pumping' in the heart.
How to use your own ginger-plants here!
Although the primary use of gingerroot (Zingiber officinale) is to ease motion sickness and nausea,
researchers in Denmark are studying its role in the prevention and treatment
of migraine headaches. The idea that ginger may ease
migraine symptoms comes from Ayurvedic medical practice, which advocates
ginger as part of the treatment for neurologic disorders, including
headaches.
|
Ginkgo
Ginkgo biloba
|
Ginkgo flavone glycosides
|
- Increases brain oxygenation,
transmission rate to nerve cells
- concentration, mental alertnes & memory
- circulation
Ginkgo supposedly also inhibits cortisol biosynthesis
|
Ginkgo Biloba and Nimodipine are probably the two
most important treatments for normalising brain
circulation in cfs/me.
It works by countering the viscosity produced by excess production of
platelet activating factor (which thickens the blood).
Dr. David Mason Brown
|
Ginseng
Panax Ginseng
|
Ginseng (Wikipedia)
|
|
Die Extrakte der Echinacea
purpurea und Panax ginseng erhöhen bei CFS- Patienten die Funktion der natürlichen Killerzellen (Ebene III-3) und die antikörperabhängige
zelluläre Zytotoxizität
ADCC (Ebene III-3).
Universität
Zürich / Dr. Jens Gaab
|
Glutathione
|
Glutathione is a peptide-like molecule naturally
synthesized in the body from three amino acids:
- L-glutamic acid
- L-cysteine
- Glycine
|
Glutathione and N-Acetyl Cysteine
Glutathione is one of the body's
most important and powerful antioxidants. Glutathione also attaches to toxic
molecules, which are then eliminated from the body (detoxification).
An article published in the journal Medical Hypothesis proposed
that glutathione, an antioxidant essential for lymphocyte function, may be
depleted in cfs-patients.
Glutathione is needed for both the immune system and for aerobic muscular
contraction. The authors proposed that glutathione depletion by an activated
immune system also
causes the muscular fatigue and myalgia associated with cfs.
(Bounous and Molson 1999)
|
Cysteine is a precursor to glutathione. It has been
hypothesized that glutathione and cysteine metabolism may play a role in
skeletal muscle wasting and muscle fatigue. The combination of
abnormally low plasma cysteine and glutamine levels, low natural killer (NK)
cell activity (with a resulting usceptibility to
viral infection), skeletal muscle wasting or muscle fatigue,
and increased rates of urea production defines a complex of abnormalities
that is tentatively called "low CG syndrome."
These symptoms are found in patients with HIV infection, cancer, major
injuries, sepsis, Crohn's disease, ulcerative colitis, cfs,
and to some extent in over-trained athletes.
(Droge and Holm 1997)
N-acetyl-cysteine is a precursor of glutathione that has been
shown to be helpful against viruses (most of the research has been with HIV
and Hepatitis infections).
(Sprietsma 1999)
(Weiss, Hildt et al. 1996)
|
Gookinaid
|
Gookinaid for low blood volume and orthostatic
intolerance. (?)
|
Homemade:
- 1 cup spring water
- 1 cup seltzer water
- 1/4 tsp sea salt
- 1/4 tsp "no salt" brand salt substitute (potassium)
- Stevia sugar substitute is allowed, sugar is not. Flavoring is allowed
Drink 3 - 4 glasses daily. Observe blood pressure response. Consider stopping
if blood pressure rises above 140/90.
|
Gookinaid.com
|
Grapefruit seed extract
|
Grapefruit seed extract is a strong antimicrobialwith proven activity against
bacteria and fungi. It also has antioxidant properties.
Grapefruit (Wikipedia)
|
- fights staph (?)
- antioxidant
- inhibit enzymes that cause inflammation
- improves circulation and capillary integrity
|
It's probably easiest and cheapest to just eat lots of
grapefruits...!
Reportedly 20 times stronger antioxidant than Vitamin C and 50 times as
powerful than vitamin E (?)
|
Green tea
|
- Polyphenol antioxidants
(A class of phytochemicals found in high concentrations in green tea, and
have been associated with heart disease and cancer prevention. The slight
astringent, bitter taste of green tea is attributed to polyphenols.
Dried leaves contain about 10% polyphenols.)
- Catechins
(A category of polyphenols.
In green tea, catechins are present in significant quantities, more
specifically:
- epicatechin (EC),
- epigallocatechin (EGC),
- epicatechin gallate (ECG)
- epigallocatechin gallate (EGCG). EGCG makes up about 10-50% of the total
catechin content and appears to be the most powerful of the catechins – with
antioxidant activity about 25-100 times more potent than vitamins C and
E.
- Theanine (amino acid that reportedly stimulates
production of alpha waves)
|
- Green Tea probably is the most cost-effective of all the
plant antioxidants!
- Makes staph aureus more susceptible to penicillin (?)
- A cup of green tea may provide 10-40mg of polyphenols and has
antioxidant activity greater than a serving of broccoli, spinach, carrots or
strawberries.
- Green Tea's ingredient EGCG is believed to be over 200
times more powerful than Vitamin E at inhibiting lipid peroxidation.
- Studies show lower arthritis, cancer and heart disease rates with regular
use of 4 cups or more per day.
- Improves hormone balance by inhibiting both 5-alpha reductase and
aromatase.
- Green Tea causes thermogenic fat loss, controls blood sugar, inhibits the
digestion of starch and prevents dental caries.
|
contains also:
Tannins - A group of simple and complex phenol, polyphenol, and
flavonoid compounds, bound with starches, and often so amorphous that they
are classified as tannins simply because at some point in degradation they
are astringent and contain variations on gallic acid. Produced by plants,
tannins are generally protective substances found in the outer and inner
tissues.
All of the tannins are relatively resistant to digestion or fermentation, and
either decrease the ability of animals to easily consume the living plant,
or, as in deciduous trees, cause shed parts of the plant to decay so slowly
that there is little likelihood of infection to the living tree from rotting
dead material around its base.
All tannins act as astringents, shrinking tissues and contracting structural
proteins in the skin and mucosa.
(For a mouth rinse you can swallow, use Xylitol and Green Tea!)(?)
Health benefits of tea (Wikipedia)
|
Guaifesin
|
|
|
300 mg twice a week
Guaidoc.com
Home.ozonline.com.au/tmarcon
|
Ho Shou Wu
|
Ho Shou Wu herb possesses properties similar to ginseng.
Ho Shou Wu is highly prized in China as an adaptogenic
herb.
A member of the buckwheat family, ho shou wu
contains Quercetin that help protect and
maintain blood vessel health.
|
|
1001herbs.com/hoshouwu
|
Hydrocortisone
(Cortisol)
|
Cortisol is a corticosteroid hormone that is involved in
the response to stress;
it increases blood pressure and blood sugar levels and suppresses the immune
system. Synthetic cortisol, also known as hydrocortisone, is used as a drug
mainly to fight allergies and inflammation.
Cortisol (Wikipedia)
|
Hypothalamo-Pituitary-Adrenal Axis Dysfunction in cfids
and the effects of low-dose hydrocortisone therapy.
Conclusions:
In conclusion, this study provides evidence that there may be
impaired adrenal cortical function in CFS on some measures and that
low-dose hydrocortisone therapy is associated with a reversal of this
HPA axis dysfunction in the minority of patients with CFS who gain benefit
from treatment.
|
Die niedrigdosierte Therapie mit Hydrokortison führt zu einer Verbesserung
der Lebensqualität. (Ebene II)
uni-züri/klipsy.ch
Article on HPA-imbalances here:
Cfsresearch.org/cfs/research/abnormalities
|
Hyperbaric oxygen therapy
(HBOT)
(First try Breathwork:
See my success with Rebirthing!)
|
Hyperbaric oxygen therapy (HBOT) is the medical use of
oxygen at a higher than atmospheric pressure.
Hyperbaric oxygen therapy (Wikipedia)
|
Among the "off label" uses of HBOT are use as a therapy for brain healing (as in stroke,
dementia, cerebral palsy), and for some infectious conditions, such as Lyme
disease and Post-polio
syndrome
|
Many bacteria thrive in anaerobic conditions so blasting
them with oxygen, kills them (?)
O2med.com
Chinook-med.com
|
Hyperthermia
- Hot immersion bath
Sauna
- FIR
(Far-Infrared Sauna)
|
(Some of the following text represents unproven
hypothesis, according to the author R.V.Konynenburg)
...I think you're right about the
FIR sauna promoting detox. Since PWCs tend to have lots of toxins stored up
as a result of
glutathione depletion over
extended times, this is probably a big factor in the FIR's benefits for PWCs.
I suspect that the FIR sauna simultaneously does several things that are
beneficial to PWCs. As you probably know,
Jim Clements emphasizes
the increase in body temperature and the resulting
increase in metabolic rate.
Sherry Rogers emphasizes the detox aspect.
I have hypothesized that it enables the sympathetic nervous system to:
Stop generating so much norepinephrine in the skin, to shut down the blood
flow there, thus lifting the demand on glutathione to dispose of the
oxidation product of norepinephrine, and also freeing up supplies of tyrosine
and phenylalanine so that the sympathetic nervous system can make
norepinephrine, to control pooling of blood in the legs, and to stop the
orthostatic intolerance.
In view of all this, I suspect that the FIR sauna will have the biggest
benefits for PWCs who have:
- a big toxin load,
- a lower than normal armpit temperature,
- orthostatic intolerance, and
- glutathione depletion.
Rich Van Konynenburg
CFSFMExperimental (at) yahoogroups
|
Douglas Lewis, N.D.,
Chair of Physical Medicine at the Bastyr College
Natural Health Clinic in Seattle, Washington, states that
a hot immersion bath, if done without raising body temperature and heart
rate too quickly or too high, can be used as an adjunctive treatment for
a "diverse number of diseases - from upper respiratory infections and
sexually transmitted diseases to cancer and AIDS."
Hyperthermia in the form of hot
baths has also proved useful in the treatment of herpes simplex and herpes
zoster (shingles).
At first the treatment aggravates the situation, but conditions improve
considerably after a short time.
It is also useful in treating the common cold and flu, as well as chronic
fatigue syndrome.
The body protects itself from viruses, bacteria, and other harmful substances
through the use of numerous defense systems.
One of these is fever. Fever raises the body's temperature above normal in an
attempt to destroy invading organisms and sweat impurities out of the system.
Fever is a highly effective and natural process of curing disease and
restoring health, and has been recognized as such for thousands of years.
Hyperthermia deliberately creates fever in the patient in order to utilize
this natural healing process.
Bodytrends.com
|
What is far infrared?
by Jim Clements
"Infrared Thermal System For
Whole-Body Regenerative Radiant Therapy"
by Dr. Aaron M. Flickstein
"Warming Up to Far Infrared"
by D.J. Fletcher
"Detox in the Sauna"
by Lawrence Wilson, MD
"Turn Up the Heat; Improve
Health with the Infra-red Sauna"
by Stefan Kuprowsky, MA, ND
"The Manual of Sauna Therapy"
by Dr. Lawrence D. Wilson MD
"Infrared Sauna"
by Dr. Jim Chan ND
"Energy Returns with Cellular Purification"
"250-Watt Infrared Heat Lamp Warnings"
Infraredsauna.net
(Medical info)
Companies that sell infrared heaters :
Thmi.com (I recommend this product!)
Buyamag.com
Chinow.com
Arrowheadhealthworks.com
(Infrared Tents)
Amazon.com
|
Inositol
Hexa-hydroxy-cyclo-hexane
|
Also
known as:
Antialopecia Factor, Cyclohexitol,
D-chiro-inositol, Dambrose, Inose,
Inosite, Inositol Monophosphate, Lipositol, Meso-inositol, Mouse Antialopecia
Factor, Myo-inositol, Vitamin B8.
Related products:
Inositol Nicotinate and IP-6.
Endogenous inositol is an essential component of cell membrane phospholipids.
It has weak lipotropic activity, and can move fat out of liver and intestine
cells (2187). Inositol has a variety of stereoisomers, including myo-inositol
and D-chiro-inositol.
Myo-inositol is the most abundant form in the central nervous system
(CNS).
Biological function varies among the isomers (2047,2048). Inositol might
reverse desensitization of serotonin receptors (2187). Limited clinical
evidence suggests exogenous inositol may have similar benefits as the
selective-serotonin-reuptake inhibitors (SSRIs) in conditions such as
panic disorder, depression, and obsessive-compulsive disorder
|
POSSIBLY
EFFECTIVE:
...when used orally for treating panic disorder with or without agoraphobia.
In one small-scale, placebo-controlled trial, inositol significantly reduced
the severity and rate of panic attacks and severity of agoraphobia compared
to placebo over 4 weeks of treatment (2184).
Large scale, long-term trials are needed to confirm inositol's potential
benefit in panic disorders.
...when used orally for treating depression. In one small-scale,
placebo-controlled trial, depressed patients receiving inositol for 4 weeks
had significant improvement, based on Hamilton Depression Rating Scale
scores, compared to placebo (2185).
In a follow-up study, patients initially responding to inositol rapidly
relapsed upon discontinuation of treatment (2026).
Large scale, long-term trials are necessary to confirm inositol's potential
benefit in depression.
|
...when used orally for treating
obsessive-compulsive disorder (OCD). In one small-scale, placebo-controlled
trial, OCD patients receiving inositol for 6 weeks had significant
improvement, based on Yale-Brown Obsessive Compulsive Scale scores, compared
to placebo (2186).
Abstracts from:
Naturaldatabase.com
1'200 mg per day of myo-inositol has been effective (within 2 weeks) for some
cfs-patients with hormonal problems.
Fights blurry vision (?)
Inositol (Wikipedia)
|
Interferon
(Alpha Interferon)
|
Interferons are natural proteins produced by the cells of
the immune systems of most animals in response to challenges by foreign
agents such as viruses, bacteria, parasites and tumor cells. Interferons
belong to the large class of glycoproteins known as cytokines.
Interferon (Wikipedia)
|
Alpha interferon is
an oral form of chemotherapy that is used to treat cancer, MS, and
hepatitis-C.
Some doctors are using it to treat ME-CFIDS-CFS, in very low doses daily for
six months.
It is supposed to boost the immune system and increases energy.
|
Someone from CFSFMExperimental-forum:
"Speaking as someone who has regained about 60% of my previous
functionality (up from about 20% 4 years ago), the best treatment I have used
is the six month course of oral alpha
interferon...
...My energy and stamina improvement were
remarkable."
|
Isoprinosine
(Imunovir)
|
|
Has both immunomodulating and antiviral properties.
It helps to treat acute and chronic viral infections.
Causes weight gain?
|
Isoprinosine acts on the immune system to restore impaired
cell-mediated response to baseline in addition to enhancing humoral
response.
It has also a direct antiviral activity.
Isoprinosine can reduce the intensity of symptoms and shorten the duration of
the viral infection.
In addition, the occurrence of complications is reduced and the frequency and
severity of recurrences is minimised.
Isoprinosine is an immunoenhancing agent in aged humans.
Anti-aging-drugs.com
|
Klonopin
(Clonazepam)
(Rivotril)
|
Clonazepam (marketed by Roche under the trade-name Klonopin® in the United States and Rivotril® in Canada and Europe) is an
anticonvulsant sedative-hypnotic anxiolytic (anti-anxiety drug), and a member
of the benzodiazepine class of drugs.
Like other benzodiazepines, Clonazepam is believed to act by simulating the
action of GABA on the central nervous system. Because of strong anxiolytic
properties and euphoriant side-effects it is said to be among the class of
'high potent' benzodiazepines with a higher risk of abuse, misuse and
dependence than other benzodiazepines.
The sedative effects of Clonazepam are relatively weak, compared to its
strong anxiolytic and anticonvulsant effectivity.
250 micrograms (0.25mg) are equivalent to 5mg Diazepam.
Klonopin (Wikipedia)
Dr. Paul Cheney Discusses the
Benefits of Klonopin
by Carol Sieverling
ImmuneSupport.com
10-12-2001
Editor’s Note: The following is based on a recent interview conducted by
Carol Sieverling with Dr. Paul R. Cheney, M.D.,
Ph.D., and the article "CFIDS Treatment: The Cheney Clinic’s Strategic
Approach" (CFIDS Chronicle, Spring 1995). Dr. Cheney gave permission to
share this information, but has not reviewed or edited it.
Many CFIDS specialists prescribe the drug Klonopin.
In the October 1999 issue of The Fibromyalgia Network, nine CFS/FM
specialists summarized their most effective treatments, and six included Klonopin. Interestingly, the three who did not are
primarily FM specialists.
Dr. Cheney prescribes Klonopin to address a
condition associated with CFIDS called "excitatory neurotoxicity."
To explain this condition to patients, he draws a line with
"seizure" on the far left and "coma" on the far right. A
big dot in the middle represents where healthy people are when awake. A dot
somewhat to the right of the middle indicates where healthy people are when
asleep – slightly shifted toward coma. He highlights in red the left portion
of the line, from seizure to the middle, and labels it "Neurotoxic State"
(damaging to the brain). He highlights in blue the right portion of the line,
from coma to the middle, and labels it "Healing State."
In CFIDS, an ongoing injury to the brain shifts patients toward seizure. A
dot to the left of the middle, marked "injury," represents the
position of CFIDS patients. This puts us in the red "Neurotoxic"
zone. When we shift toward seizure, we often experience "sensory
overload." It’s as if our brain’s "radar" is too sensitive.
Our neurons (nerve cells) are sensing stimuli and firing when they should
not. This causes amplification of sensory input. Light, noise, motion and
pain are all magnified. At the beginning of their illness, many patients
report feeling exhausted, yet also strangely "wired." The
"wired" feeling is the slight shift towards seizure that occurs as
a result of the excitatory neurotoxicity.
Cheney frequently uses the term "threshold potential" when
discussing excitatory neurotoxicity. (Think of the threshold - bottom - of a
doorway. The lower it is, the more accessible it is. When it is at floor
level, everything can enter. When it is raised, access is restricted to
taller people. If it is too high, no one can enter.) Threshold potential
refers to how much stimulus it takes to make neurons fire. If the threshold
potential is too low, even slight stimulation is "allowed to enter"
and is detected by the neurons. This causes the neurons to fire, resulting in
sensory overload. If the threshold is dropped to nothing, all stimuli get
through and the neurons fire continuously, resulting in a seizure. If the
threshold is raised, only stronger stimuli can make neurons fire. A healthy
person’s threshold potential naturally rises at bedtime, promoting sleep. If
the threshold potential is too high, you feel drugged or drowsy. If the
threshold potential is raised extremely high, coma results.
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Two receptors in the brain, NMDA and GABA, determine the
threshold potential. During the waking hours of a healthy person, NMDA and
GABA should be equally active. This balances the person in the middle of the
seizure/coma continuum. NMDA stimulates, and GABA inhibits. If NMDA
increases, one moves toward seizure. If GABA increases, one moves toward
coma.
In CFIDS, NMDA is more activated
than GABA, lowering the threshold potential. This causes neurons to fire with
very little stimulation, resulting in sensory overload. This condition of
excitatory neurotoxicity is dangerous. Dr. Cheney emphasizes that in an
attempt to protect itself, the body will eventually kill neurons that fire
excessively. He states that brain cell loss can result if this condition
isn’t addressed.
How can the brain be protected against excitatory neurotoxicity? Klonopin. This long acting
benzodiazepine has been Dr. Cheney’s most effective drug for CFIDS over the
years. He believes that Klonopin and the supplement
magnesium may be two of the most important treatments for CFIDS patients
because of their neuroprotective qualities. He recommends two or more 0.5 mg
tablets of Klonopin at night. Paradoxically, very
small doses (usually a quarter to a half a tablet) in the morning and
mid-afternoon improve cognitive function and energy. If the daytime dose is
low enough, you’ll experience greater clarity and think better. If the
daytime dose is too high, you’ll become drowsy. Adjust your dose for maximum
benefit, taking as much as possible without drowsiness. Adjust the morning
dose first, then take the same amount mid-afternoon if needed, then take
three to four times the morning dose at bedtime. Dr. Cheney recommends
doubling the dose during severe relapses.
Dr. Cheney most frequently prescribes the combination of Klonopin
and Doxepin, along with the supplement "Magnesium Glycinate Forte."
Magnesium Glycinate alone is a good choice for the more budget minded(www.ImmuneSupport.com sells it as "Magnesium
Plus".) A common dosage of magnesium is 200 mgs at bedtime. Too much
magnesium can cause diarrhea, though glycinate is usually the best tolerated
form.
Cheney prescribes Doxepin in the form of a commercial elixir (10mg/ml). At
low doses, this tricyclic antidepressant acts as a very potent antihistamine
and immune modulator. Doxepin acts synergistically with Klonopin
to assist sleep, and may improve pain. Patients tend to be very sensitive to
Doxepin, which can cause morning fog and fatigue if the dose is too high (5
to 10 mg or higher). He recommends starting at two drops a night and
gradually increasing the dose until "morning fog" becomes a
problem. Most patients can’t tolerate more than half a cc.
On a handout entitled "Neuroprotection via Threshold Potentials,"
Cheney lists six substances that can protect the brain. Under the category
"NMDA Blockers" Cheney lists:
1. Parenteral magnesium and taurine (intramuscular injections of magnesium
and taurine, usually given with procaine) 2. Histamine blockers (Doxepin
Elixir) Under the category "GABA Agonists" (increases GABA) Cheney
lists: 3. Klonopin 4. Neurontin 5. Kava Kava 6. Valerian Root
|
Klonopin is taken "day and night"; Neurontin
"night, or day and night"; kava kava
“daytime only”; and valerian “nighttime only.” The first four are by
prescription, the last two are herbs. In my limited experience, only certain
patients are put on magnesium/taurine injections, and then only for a limited
period before switching to oral supplements.
Many myths abound concerning Klonopin. When asked about these myths, Dr. Cheney shared
the following information.
MYTH NUMBER ONE: THE GENERIC IS JUST AS GOOD.
When the generic Clonazepam came on the market, many patients switched to it
because it was less expensive than Klonopin. Cheney
then began hearing that most patients had to take more Clonazepam to get the
same effect. Generics aren’t exactly identical to the original products, and
with most drugs the slight variations don’t matter. However, most CFIDS patients
can tell the difference between Klonopin and its
generic form, Clonazepam. Most find Klonopin to be
more effective.
MYTH NUMBER TWO: KLONOPIN IS ADDICTIVE.
Dr. Cheney was adamant that Klonopin is not
addictive. In treating thousands of patients, he has never seen a patient
become addicted to Klonopin. He reviewed the
definition of addiction, stating that it involves: (1) psychosocial
disruption, (2) accelerated use, (3) inappropriate use, and (4) drug seeking
behavior.
Dr. Cheney said a case might be made that Klonopin
is habituating. It’s true that it can’t be stopped suddenly. You must taper
off of it gradually. However, he was cautious about even calling it
habituating. The process of tapering off a drug is not the same thing as
withdrawal, a term that implies addiction.
Dr. Cheney said to keep in mind that Klonopin is
given for a physiological problem – excitatory neurotoxicity. It’s prescribed
to adjust the threshold potential: to keep neurons from firing
inappropriately and being destroyed. He stressed that Klonopin
should never be given unless you intend to raise the threshold potential. He
stated, "Problems arise when you begin to use benzodiazapines
for reasons other than threshold manipulation." However, CFIDS patients
have a "threshold potential aberration" and need Klonopin (or something similar) to avoid brain injury.
Dr. Cheney has never seen a recovered patient have difficulty coming off Klonopin. He stated, "When you no longer need the
drug, coming off it is very easy."
On the other hand, trouble arises when someone who still has an injured brain
tries to come off Klonopin. It’s like a thyroid
patient stopping their thyroid medication. Dr. Cheney warned, "All hell
breaks loose". However, it’s not because the drug is addicting, and it’s
not withdrawal. The condition still exists, and the body lets you know it has
a legitimate physical need for the drug. Cheney stated, "When a CFIDS
patient who is still experiencing the underlying mechanisms of brain injury
goes off Klonopin, there is a burst of excess
neural firing and cell death. That’s the havoc we hear about that is
mistakenly called withdrawal."
MYTH NUMBER THREE: KLONOPIN DISRUPTS STAGE 4 SLEEP.
Dr. Cheney said that he honestly doesn’t understand this concern. He believes
Klonopin might disrupt the sleep of people who take
it for conditions other than the threshold potential aberration found in
CFIDS. He also acknowledged that if you are looking just for drugs to
facilitate sleep, Klonopin is certainly not the
first one to come to mind, nor should it be used to induce sleep in
"ordinary" patients. It’s not a sleep drug per se. However, a large
part of the sleep disorder of CFIDS is excitatory neurotoxicity and the
resulting shift toward seizure. If you treat this condition with Klonopin, then you have treated a large part of the sleep
disorder in CFIDS. Most importantly, he said he simply does not see stage 4
sleep disruption in his patients on Klonopin.
Towards the end of this discussion on Klonopin,
Cheney smiled, and remarked, "But suppose I’m wrong about the brain
injury and the threshold potential aberration and the shift toward seizure?
What if I’m wrong about your need for Klonopin? I’m
absolutely sure I’m right, but what’s the worst case
scenario? Do you know what long-term studies on Klonopin
have shown? Reduced incidence of Alzheimer’s Disease. Alzheimer’s Disease is
a complicated and convoluted way of knocking out your neurons, and Klonopin protects your neurons. Now it’s believed that Klonopin didn’t actually stop Alzheimer’s. It just
delayed its onset so long that everyone died of something else before they
ever got it - which is to say you won’t get Alzheimer’s. You’ll die of
something else first."
The last question Cheney addressed concerned the dose: what happens if the
dose is too high? He said the only down side was that if you took a little
too much (we are not talking overdose here) it would shift you toward coma on
the continuum. It would shut your brain down to some degree, and thus impact
your ability to function. This is inconvenient, but it’s not harmful. In
fact, it shifts you into the "healing state" on the continuum. You
may feel like a zombie, but your brain is protected and your neurons are not
getting fried. However, not being able to function isn’t an option for most
of us, so we need to find the maximum dose that doesn’t make us drowsy.
Dr. Cheney emphasized that Klonopin, Doxepin, and
magnesium are very, very good at protecting the brain from cell death due to
excess firing. However, they can’t stop the underlying mechanisms of CFIDS
that are injuring the brain in the first place.
Though it can’t stop the underlying mechanisms causing the injury, Klonopin can protect your brain and keep your neurons
from being destroyed. Then, as Cheney put it, "When you come out on the
other side of this, you’ll have more of your brain left."
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Kombucha
|
Kombucha is the Western name for a fermentation of
sweetened tea using lactobacilli and yeast cultures.
The tea contains a symbiosis of yeast species and acetic acid bacteria,
mostly Bacterium xylinum. Species of yeast found in
the tea can vary, and may include: Brettanomyces bruxellensis,
Candida stellata, Schizosaccharomyces pombe, Torulaspora delbrueckii and
Zygosaccharomyces bailii.
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Some studies have found potent anti-stress,
hepato-protective, antioxidant and immunomodulating properties in Kombucha
preparations given to rats. However, rare, serious health problems have also
been attributed to drinking or preparing Kombucha.
Kombucha (Wikipedia)
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Kutapressin
|
Kutapressin is an immune modulator and a broad spectrum anti-viral.
It is a porcine(pig) liver extract. There is very little published research
on it.
- Effective against Epstein-Barr virus
- Effective against against human
herpes-virus-6 (HHV6)
Lassesen.com/cfids/kutapressin
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(Similar effects as Ampligen?!) (?)
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Lactoferrin
(Lactotransferrin)
(Colostrum)
(Whey Protein)
|
Lactotransferrin (LTF) is a
globular multifunctional protein with antimicrobial activity (bacteriocide, fungicide), is part of the innate defense,
mainly at mucoses.
LTF is found in milk and many mucosal secretions such as tears and
saliva.
LTF is also present in secondary granules of PMN and also is secreted by some
acinar cells. LTF can be purified from milk or produced recombinantly. Human
colostrum has the highest concentration, followed by human milk, then cow
milk.
Lactoferrin (Wikipedia)
Aka: Bovine lactoferrin
Lactoferrin is a protein belonging to the iron
transporter family that occurs naturally in several bodily fluids such as
tears, saliva,mucus and
milk. Found in mother's milk produced 24 to 48 hours after birthing,
lactoferrin provides the body's first defense against disease.
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Colostrum,
in lactoferrin is the pre-milk fluid produced by mammals immediately after
birthing. With high protein, immunoglobulin and antibody content, it's nature's perfect food contributing to newborn's defense
system.
Fights staph
Anti-microbial (?)
Covers many including
coag negative epidermidis and yeast (?)
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Whey protein is
comprised of four major protein fractions and six minor protein fractions.
The major protein fractions are:
- beta-lactoglobulin,
- alpha-lactalbumin,
- bovine serum albumin,
- immunoglobulins.
Each of these components have important disease-fighting effects.
Lactoferrin, in particular, has been shown to have significant
antiviral activity.
(van der Strate, Beljaars
et al. 2001)
(Swart, Kuipers et al. 1998)
(Harmsen, Swart et al. 1995)
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Lysine
(L-Lysine)
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Lysine is one of the 20 amino acids normally found in
proteins. With its 4-aminobutyl side-chain, it is classified as a basic amino
acid, along with arginine and histidine.
It is an essential amino acid, and the human nutritional
requirement is 1–1.5 g daily.
A deficiency in lysine can result in a deficiency in niacin (which is a B
Vitamin). This can cause the disease pellagra.
Lysine can also be used as a nutritional supplement to help against herpes.
Lysine (Wikipedia)
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Lysine is lacking in many diets, particularly vegetarian.
Both lysine and arginine contribute to immunity and have
antiviral properties. Proteins (meats, fish and cheese) usually contain
slightly more lysine than arginine, with eggs containing equal amounts.
Supplementation with equal amounts of lysine and arginine is recommended for
those considering this therapy.
Dose : 1 x 500 mg capsule of each can be taken once
or twice daily.
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Linus Pauling recommended
Lysine with
Vitamin C & L-Proline to prevent formation
of Lp-a, which contributes to arterial plaque
formation.
Dose : 3 x 1g daily (for 3 months)
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Maca
Lepidium meyenii
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Maca (Lepidium meyenii)
is a biennial plant or annual plant grown in very high parts of the Andes in
Peru for its enlarged hypocotyl, used as a root vegetable. Botanically this
herb is related to turnip and radish.
The part of the radish that is eaten is also known as a hypocotyl. Maca is
the only member of its genus with a fleshy hypocotyl. Maca's hypocotyl is
roughly 10-15 cm long and 3-5 cm long in each plant.
The plant spreads entirely by seeds which germinate within 5 days given good
conditions and have no dormancy.
Maca (Wikipedia)
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Maca root
- glucosinolates which have a positive effect on
fertility.
- Proteins, as polypeptides, make up 11 per cent of the maca root;
- calcium makes up 10 percent - magnesium and potassium are present in
significant amounts.
- iron, silica and traces of iodine, manganese, zinc, copper and sodium.
Vitamins in maca are thiamine, riboflavin and ascorbic acid.
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Menopausal symptoms: hot flashes,
tender breasts, sleeplessness and emotional upsets, "brain fog",
vaginal dryness.
Osteoporosis: significant bone rebuilding, improvement in bone density.
Energy booster: Balances the endocrine system - thyroid, pituitary and
adrenal glands.
Male impotence
Chronic Fatigue Syndrome
Period problems: Pain, PMS, flooding and/or scant flow.
Healalliance.com/macaroot.html
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Magnesium
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Food Sources of Magnesium:
Green vegetables such as spinach provide magnesium because the center of the
chlorophyll molecule contains magnesium. Nuts, seeds, and some whole grains
are also good sources of magnesium.
Although magnesium is present in
many foods, it usually occurs in small amounts.
As with most nutrients, daily needs for magnesium cannot be met from a single
food. Eating a wide variety of foods, including five servings of fruits and
vegetables daily and plenty of whole grains, helps to ensure an adequate
intake of magnesium.
The magnesium content of refined foods is usually low. Whole-wheat bread, for
example, has twice as much magnesium as white bread because the
magnesium-rich germ and bran are removed when white flour is processed.
The table of food sources of magnesium suggests many dietary sources of
magnesium.
Water can provide magnesium, but the amount varies according to the water
supply. "Hard" water contains more magnesium than "soft"
water. Dietary surveys do not estimate magnesium intake from water, which may
lead to underestimating total magnesium intake and its variability.
Following are some foods and the amount of magnesium in them:
- spinach (1/2 cup) = 80 milligrams (mg)
- peanut butter (2 tablespoons) = 50 mg
- black-eyed peas (1/2 cup) = 45 mg
- milk, low fat (1 cup) = 40 mg
Magnesium (Wikipedia)
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One group of researchers reported that individuals with
CFS were found to have lower red cell magnesium concentrations compared to
matched controls. In a double-blind study, 32 patients with chronic fatigue
syndrome were either given 50% magnesium sulfate in a 1 gm/2 ml I.M. weekly
injections or a placebo of 2 ml of injectable water.
Patients treated with magnesium claimed to have improved energy levels, better
emotional states,
and less pain.
Twelve of 15 patients reported benefiting from the therapy and 7 patients
reported significant energy improvement.
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In the placebo group only 3 of 17
patients said they felt better and one patient had improvement in energy. Red
cell magnesium normalized in all patients receiving the injection, but only 1
patient returned to normal in the placebo group.
The authors conclude that chronic fatigue syndrome patients have slightly
lower magnesium levels than healthy controls and that magnesium therapy
appeared to be of benefit. They cautioned that their trial was small and only
had a follow-up of 6 weeks.
Cox IM, et al. 1991
Red Blood Cell Magnesium and CFS.
Magnesium führt kurzfristig zu einer Verbesserung in physischen, physiologischen, psychischen und die Lebensqualität
betreffenden Variablen (Ebene II).
uni-züri/klipsy.ch
Dr. Rosenbaum:
"I have found that a cocktail of calcium 600 to
800 mg and magnesium 300 to 500 mg taken before
bedtime has a relaxant effect that is very useful for sound sleep
and to prevent restless legs."
Immunesupport.com/article
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Maitake
(Hen of the Woods)
Grifola frondosa
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Hen of the Woods (Grifola frondosa referring to a mythical beast which is half-lion
and half-eagle), also known as Sheep’s Head and Maitake (pronounced my-tah-keh), is an edible
mushroom.
It has a rippling form with no caps, and grows in clusters at the foot of oak
trees, giving it an image of dancing butterflies, and thus the Japanese named
it "maitake", literally meaning "dancing mushroom".
Hen of the Woods should not be confused with the similarly named edible
bracket fungi, Chicken of the Woods (Laetiporus sulphureus), also known as "sulphur
shelf". Some people prefer calling it Chicken Mushroom precisely so that
they don't confuse it with Hen of the Woods.
Maitake (Wikipedia)
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The underground tubers from which Hen of the Woods arises
has been used in Traditional Chinese and Japanese medicine to enhance the
immune system. Researchers have also indicated that whole maitake has the
ability to regulate blood pressure, glucose, insulin, and both serum and
liver lipids, such as cholesterol, triglycerides, and phospholipids, and may
also be useful for weight loss.
Maitake is rich in minerals (such
as potassium, calcium, and magnesium), various vitamins (B2, D2, Niacin, and
C), fibers and amino acids. The active constituent in maitake for enhancing
the immune actively has been identified in the late 1980s to be the
protein-bound polysaccharide compound, beta-glucan, an ingredient
found especially in the family of polyporaceae.
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Activates macrophages and variety of other immune cells.
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Melatonin
|
Melatonin, 5-methoxy-N-acetyltryptamine, is a hormone
produced by pinealocytes in the pineal gland
(located in the brain) and also by the retina and GI tract.
It is naturally synthesized from the amino acid tryptophan (derived
from serotonin) by the enzyme 5-hydroxyindole-O-methyltransferase.
Most of biological effects of melatonin are produced by its binding to and
action on melatonin receptors [1].
Melatonin is also synthesized by various plants, such as rice, and ingested
melatonin has been shown to be capable of reaching and binding to melatonin
binding sites in the brains of mammals.
Melatonin (Wikipedia)
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Treatment with DHEA or
melatonin alone, as well as together, prevented the
reduction of B- and T-cell proliferation as well as of Th1 cytokine secretion
caused by retrovirus infection.
Supplementation also suppressed the elevated production of Th2 cytokines
stimulated by retrovirus infection.
(Zhang, Araghi-Niknam et al. 1999)
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Milk thistle
Silybum marianum
Silybum eburneum
Silybum × gonzaloi
|
By far the more widely known species is silybum marianum, which is known to give some remedy for
liver diseases : cirrhosis, jaundice and
hepatitis.
Its potent extract is used in medicine under the name silymarin. Another
extract, silibinin or a derivative, is used against
poisoning by amanitas, such as the Death Cap (Amanita phalloides) and the Fly
Agaric (Amanita muscaria).
Milk thistle (Wikipedia)
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Powerful antioxidant,
promoting liver & kidney function.
Inhibits excess cell proliferation in cancer, atherosclerosis & aging
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(for food use : the leaves and
flowers are eaten as a vegetable)
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Mito cocktail
|
Mito "cocktail" consists
of relatively large amounts of:
- L-carnitine
- CoQ10
- D-Ribose (Possibly)
- Vitamin B12 (Cyanocobalamin)
- Vitamin B7
(Biotin)
- Several other nutrients
|
Mito cocktail: Symptoms of CFS generally resemble those of
metabolic and mitochondrial disorders. Mito cocktail consists of a
combination of supplements which is sometimes used to treat ME-CFIDS-CFS.Aswith
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mitochondrial disorder, it is believed that large amounts
(eg, 2-10g/day l-carnitine) are necessary to have a
significant effect. Smaller amounts of these nutrients might not be helpful.
Chronic fatigue syndrome / Mito cocktail (Wikipedia)
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MSM
(Methylsulfonylmethane)
|
Methylsulfonylmethane (MSM, or dimethylsulfone) is an
organic sulfur compound with the chemical formula CH3SO2CH3. It belongs to a
class of compounds known as sulfones. It is found naturally in some primitive
plants and is present in small amounts in many foods and beverages...
...MSM is marketed as a dietary
supplement. However, the claims of proof of its beneficial effects are
disputed and published research on the compound's effects is considered
thin...
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Claims of beneficial effects
MSM has been purported to have anti-inflammatory
MSM (Wikipedia)
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NAC
(N-acetylcysteine)
|
N-acetylcysteine is a chemical, commonly called NAC,
produced by the body that enhances the production of the molecule glutathione,
a powerfulantioxidant.
NAC is a thiol, in which the hydrogen atom can act to reduce free radicals.
In the United States, NAC is
available as an over the counter supplement in
health stores and in a prescription-only oral solution as Mucomyst® (Bristol-Myers Squibb) or Mucosil® that can be ingested or aerosolized and
inhaled.
Outside of the United States, it is available in pharmacies as an over the counter oral medicine and also available in an
intravenous form as Parvolex®.
NAC has different uses in the treatment of medical conditions:
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NAC is used as a mucolytic ("mucus dissolving")
agent to help break up the thick mucus often present in people suffering from
respiratory ailments (e.g. flu, bronchitis,
sinusitis), which it accomplishes by the splitting of disulphide
bonds in mucoproteins.
In more severe cases, like chronic respiratory conditions, it is given as an
inhaled mist.
Studies indicate that NAC can also be used to lessen the symptoms and
duration of the flu and the common cold.
It is used by AIDS patients,
whose glutathione levels are depressed, and also by bodybuilders, whose
intense training causes temporary lower levels of glutathione.
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NAC may also be useful in the treatment of cocaine
addiction and in the removal of mercury from the body.
Studies suggest that NAC, taken together with Vitamin C and B1 can be used to
prevent and relieve symptoms of veisalgia (hangover
caused by alcohol).
NAC (Wikipedia)
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NADH
(Nicotinamide adenine
dinucleotide)
|
Nicotinamide adenine dinucleotide (NAD) and nicotinamide
adenine dinucleotide phosphate (NADP) are two important coenzymes found in
cells.
NADH is the reduced form and NAD+ is the oxidized form of NAD.
NADH (Wikipedia)
NADH is the reduced form
(energy rich) of the biological compound called coenzyme #1.
It is called coenzyme #1 based on its level of importance to the body. It's
the highest ranking coenzyme in the body.
NADH is the body's most potent biological antioxidant. (?)
Coenzyme #1 is the substance
within the cell with the highest reduction power of all biologically active
compounds.
|
A recent randomized, double-blind,
placebo-controlled crossover study examined the use of NADH with CFS.
26 eligible patients diagnosed with cfs received
either 10 mg of NADH or placebo for a 4-week period.
8 of 26 (31%) responded favorably to NADH in contrast to 2 of 26 (8%) to
placebo.
Based upon these encouraging results the authors decided to conduct a larger
study to establish its efficacy in cfs. (Forsyth,
Preuss et al. 1999)
NADH (5 to 10 mg per day) is most effective when taken in the
morning 30 minutes before breakfast.
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In terms of biochemistry, aging is a transition from an
energy rich state to an energy poor state. An energy rich state is also
called the reduced form. An energy poor state is also called the oxidized
form.
An analogy would be oxidized steel (or rusted metal) is the poorer of the two
states of the metal. In biology it is much the same way:
If you don't feel any effect on 5mg per day, increase to 15mg per day. The
effect of NADH should be noticeable immediately. (?)
NADH ist bei cfs-Patienten von einem allgemeinen Nutzen, was die Lebensqualität betrifft (Ebene
II)
uni-züri/klipsy.ch
Immunesupport's NADH products
Nadh.com
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Nefazodon
Nefazodone hydrochloride
|
Nefazodone hydrochloride (Serzone®)
is an antidepressant drug marketed by Bristol-Myers Squibb.
Its sale was discontinued in 2003 in some countries, due to the small
possibility of hepatic (liver) injury, which could lead to the need for a
liver transplant, or even death.
It is still prescribed and sold in the United States.
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Nedazodone's claimed advantages over other antidepressants available
at the time included reduced possibility of disturbed sleep or sexual
dysfunction, and ability to treat some patients who did not respond to other
antidepressant drugs.
Nefazodon
(Wikipedia)
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Nefazodon bewirkt eine
Verbesserung psychischer Variablen.
(Ebene III-3).
uni-züri/klipsy.ch
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Nettle (Stinging)
Urtica dioica
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The Stinging nettle (Urtica dioica and sometimes jaggy
nettle or burning weed) is a herb native to Europe,
Asia, and North America, the best known member of the nettle genus Urtica.
Stinging Nettle (Wikipedia)
|
Nettles have a long history of use in the home as a herbal remedy and nutritious addition to the
diet[K].
A tea made from the leaves has traditionally been used as a cleansing tonic
and blood purifier so the plant is often used in the treatment of hay fever,
arthritis, anaemia etc[254].
The whole plant is antiasthmatic, antidandruff,
astringent, depurative, diuretic, galactogogue, haemostatic, hypoglycaemic and
a stimulating tonic.
Pfaf.org/urtica-dioica
|
contains 5-HTP
(increases vivid night dreams?)
|
Neurotropin
|
Neurotropin is a “non-protein extract of cutaneous tissue from
rabbits inoculated with vaccinia virus”
Masscfids.org
Neurotropin is a medication that is currently used
in Japan to treat RSD and other painful conditions.
(RSDS = Reflex Sympathetic Dystrophy Syndrome)
Rsdhope.org
|
A 28-year-old male visited an outpatient department due to
general fatigue and pain involving the entire body. He did not suffer from
fibromyalgia, but he was diagnosed with CFS.
At the initial visit, he
complained of lack of concentration, memory decline, frequent urination,
insomnia and occasional difficulty of emotional control, as well as general
fatigue and pain involving the entire body. Four tablets of Neurotropin per day alone were administered. General
fatigue and pain were gradually alleviated one week later. His sleep
condition, concentration power, and memory also improved two weeks later.
|
Medication was discontinued from
11 weeks based on the patient's judgment as he felt little general fatigue
and pain involving the entire body. Treatment was completed 3 months later.
The symptoms disappeared and did not recur five months after the
discontinuation of Neurotropin. He was looking for
a job without fatigue and pain 8 months later (5 months after the cessation
of treatment).
Efficacy of neurotropin
in chronic fatigue syndrome (Immunesupport.com)
|
Nimodipine
|
Nimodipine (marketed by Bayer
as Nimotop®) is a dihydropyridine
calcium channel blocker originally developed for the treatment of high blood
pressure.
Nimodipine (Wikipedia)
Nimodipine is a calcium channel blocker.
It works by normalising the blood
circulation in the brain, especially through the smallest blood
vessels.
It also works by relieving areas of localised
vessel spasm in the brain decreasing the vascular headaches
sometimes associated with ME-CFIDS
|
In ME-CFIDS there can be reduced
blood pressure due to the neurally
mediated hypotension found in many patients.
Neurally mediated hypotension is
where the blood drains from the head causing parts of the brain to have
inadequate circulation.
This is why ‘brain fog’ often occurs.
|
The re-stabilisation of the brain
circulation releases the neurotoxins, which have become trapped in the brain
in a controlled fashion.
Restoring the circulation to the brain and to the pituitary gland allows
hormones to reach various glands in the body.
This enables the body’s distribution system to work as intended, which is
vital in order to take oxygen, nutrients and any medication where it is
needed. This is analogous to clearing blockages from a railway track to allow
the trains to operate again.
Dr.
David Mason Brown
Dr. Goldstein also recommends it.
|
Nootropics
|
Nootropics, or so-called "smart drugs," are
substances alleged to increase the faculties of the mind.
The word derives from noos or mind and tropos, a bend. Proponents claim that these
substances enhance mental performance in a variety of
ways, bolstering cognition, lucidity, memory, mood, oxygen and
glucose utilization, blood circulation in the brain, or a combination of
these or other factors.
Nootropics (Wikipedia)
|
- Piracetam (Nootropil)
- Aniracetam
- Oxiracetam
- Pramiracetam
- Pyritinol (Enerbol)
- Ergoloid mesylates (Hydergine)
- Galantamine
- Selegiline
- Centrophenoxine (Lucidril)
- Desmopressin (DDAVP)
- Nicergoline
- Vinpocetine
- Picamilon
- Vasopressin
- Milacemide
|
|
Olive leaf extract
Olea europea
|
- Oleuropein
Raw green olives, direct from the tree, product sources unknown, are very
bitter and have high concentrations of oleuropein.
- antibacterial
- antiviral
- antiparasitic
- antifungal
- lowers LDL levels
- stimulates phagocyte growth
- increases nitric oxide (NO)
|
Benefits:
- vasodilator activity
- antimicrobial agent for treatment of intestinal or respiratory tract
infections
- potentiates the macrophage
mediated response
- antiviral agent
- strong antioxidant
- antibacterial and antifungal
Lassesen.com/supplements
|
But it can lower blood pressure,
so be careful and add licorice if necessary. Up to 10 capsules per day is
safe. Take at bedtime since the effect tends to deepen sleep.Olive leaf extract kills viruses by
inhibiting their replication and increases conversion of T4 to T3.
An effective dose of oleuropein increases body temperature 1/2 to 1 degrees F
within 1 hour after you take it. Besides increases in body temperature,
sometimes people have flu like symptoms and mild headaches due to a die-off
effect from killed-off fungal infections.
Dose : Is supposed to work at low doses, yet is
believed to be nontoxic even at high doses.
(note that to clear an infection it needs to be
taken in very high doses ie 4x 500mg capsules 4
times a day)
|
Ondansetron
(Zofran)
(Emeset)
(Emetron)
(Ondemet)
|
Ondansetron is a serotonin
5-HT3 receptor antagonist used mainly to treat nausea and vomiting
following chemotherapy.
Its effects are thought to be on both peripheral and central nerves.
One part is to reduce the activity of the vagus
nerve, which is a nerve that activates the vomiting center in the medulla
oblongata, the other is a blockage of serotonin receptors in the
chemoreceptor trigger zone. It does not have much effect on vomiting due to
motion sickness. This drug does not have any effect on dopamine receptors or
muscarinic receptors.
Ondansetron (Wikipedia)
|
|
Ondansetron bewirkt eine Verminderung der Erschöpfung und einen Anstieg der Leistungsfähigkeit
(Ebene III-3).
uni-züri/klipsy.ch
|
Oregano Oil
Orgianum compactum
Orgianum vulgare
|
Oregano (Origanum vulgare) is a spicy, Mediterranean,
perennial herb, particularly common in Greek and Italian cuisines.
It is the leaves that are used in cooking, and the dried herb is often more flavourful than the fresh.
Oregano is high in antioxidant activity, paticularly
due to a high content of phenolic acids and flavonoids.
Additionally, oregano has demonstrated antimicrobial activity
against foodborned pathogens such as Listeria
monocytogenes.
Both of these characteristics may be useful in both health and food
preservation.
Oregano (Wikipedia)
|
- anti-viral
- anti-fungal (yeast and candida problems)
- anti-microbial
- anti-tissue agent (meaning it halts coughs and eases spasticity of the lung
tubules)
- mucolytic (means it helps thin mobilized mucous)
- anti-spasmodic (meaning it obliterates tightness and spasms of muscles
- anti-parasitic
|
Carvacrol levels in Origanum vulgare can be as high as 85%
in some plants.
Reportedly beneficial properties for the following conditions:
digestion, depression, flu, constipation, rashes, brain fog, lung fungus, toe
and fingernail fungus, head lice, aching joints and muscles, warts, athlete’s
foot, eczema, flu, headaches, toothaches, ear infection, fevers, allergies,
burns, bleeding, fatigue, arthritis, sprains, back pain, colds, when sprayed,
cleans air, kills bugs on plants, kills fleas, lyme
disease, canker sores, gastrointestinal/colitis/diarrhea, e.coli
and so on...
|
Oxytocin
|
Oxytocin is a hormone, found in mammals, which in humans
is released mainly after stimulation of the nipples or distention of the
vagina and which facilitates birth and breastfeeding. It is also involved in
orgasms as well as in bonding and the formation of trust between people.
- Various anti-stress functions: reducing blood pressure
and cortisol levels, increasing tolerance to pain, reducing
anxiety.
- Oxytocin may play a role in encouraging "tend and befriend", as
opposed to "flight or fight", behavior, in response to stress.
- It inhibits the development of tolerance to various addictive drugs
(opiates, cocaine, alcohol) and reduces withdrawal symptoms, at least in
animal tests. (Kovacs 1998)
Oxytocin (Wikipedia)
|
"In a male and in a non-pregnant female,oxytocin increases blood flow to
the eye, to the brain, and to muscle.
The end result of that is, in a non-pregnant individual it tends to make the
skin feel warmer and the body feel warmer. You think more clearly and
you see more clearly. It can be remarkable. I can give the patient a
shot of oxytocin in the hip and five minutes later they will say, "I
haven’t seen this clearly, I haven’t felt this well in months." It
doesn’t work for everybody, but when it does, it is quite miraculous and can
be a long term therapy."
From Dr. Charles Lapp's Article on
immunesupport.com
|
Dr. Goldstein's recommendation
(?)
Somebody went to a talk about fibro (he believes cfids
is fibro) given by Dr. Michael Powell in Sacramento
yesterday, check out his site:
Fmtlc.com
|
Pancreatic enzymes
|
The pancreas produces enzymes that break down all
categories of digestible foods (exocrine pancreas) and secretes hormones that
affect carbohydrate metabolism (endocrine pancreas).Thepancreas
|
is the main source of enzymes for digesting fats (lipids)
and proteins - the intestinal walls have enzymes that will digest
polysaccharides.
Pancreas (Wikipedia)
|
|
Piracetam
(Nootropil)
(Myocalm)
|
Piracetam (brand name: Nootropil®, Myocalm®), is a cerebral function regulating drug
which is claimed to be able to enhance cognition as well as slow down brain
aging.
Piracetam is a cyclic derivative of GABA .
It is one of the racetams, and is similar to the amino acid pyroglutamate.
Piracetam (Wikipedia)
|
Jump to other nootropics
|
Piracetam works best when taken with choline. Take 800 mg
doses, but none several hours before bedtime. It can be consumed safely at up
to 8000 mg per day. An initial dose of 2400 mg followed by daily morning
doses of 800 mg is a good general regimen. It may take several weeks to see
effects. Taper off slowly. (As with Klonopin)
Pharmacymex.com
Folkarts.com/idef/pharmacies.htm
Uta.fi/~samu/nootropics_resources.html
(Other cognitive enhancers)
|
Prednisone
|
Prednisone is a synthetic corticosteroid drug
which is usually taken orally and can be used for a large number of different
conditions.
It has a mainly glucocorticoid effect. Prednisone is a prodrug that is
converted by the liver into prednisolone, which is the active drug and a
steroid.
Prednisone is particularly effective as an immunosuppressant and
affects virtually all of the immune system.
It can therefore be used in autoimmune diseases, inflammatory diseases (such
as asthma and Crohn's disease), various kidney diseases including nephrotic
syndrome, and to prevent and treat rejection in organ transplantation.
Prednisone (Wikipedia)
|
From a discussion forum:
"...This is remarkable, glad to hear you are getting some life back! I
wish it had been that simple for me. I took Prednisone for awhile, I did feel better on it at first, but after a
month the good effects all wore off and and I
really didn't want to keep raising the dose and take the risks ass'd with it.
After I stopped it my pain and fatigue were a lot worse than before I started
it and took me many months to get back to baseline.
I took 5mg Prednisone in the AM. It did make me feel better, but can't say
that it came close to curing me, then all effects seemed to wear off
completely..."
|
From another discussion forum:
"...I have been following the Jeffries protocol since February and
noticed huge improvements on 20 mg h/c every day but I was still getting
hypoglycemic drops and didn't feel good on getting up. My doctor switched me
to Prednisone 2.5mg 9 pm and the same dose 8 am.
This has made a HUGE difference and I can say that I no longer have cfs.
The reason is that Prednisone is longer acting, the problem I had with the
h/c is that it gives you constant highs and lows even at 20 mg a day whereas
the Prednisone doesn't do this.
I can do a huge amount each day
with only short sit downs to recover. By the evening I am sometimes quite
tired but usually can take my dog out for a 30 minute
walk. I sleep through the night nearly every night and this hasn't happened
for 10 years.
In addition to the 5mg Prednisone I have to take 2 grains of Armour for my thyroid. These 2 meds have given me my life
back and everyday I can lead a more or less normal
life (I have high antithyroglobulin antibodies).
Dr. Jeffries proved with thousands of patients over 30 years or
more that there were no ill effects as long as one stuck under 20 mg
hydrocortisone. In fact he found that his patients
on this dose were healthier than his other patients. After all
if our bodies are not making enough cortisol all we are doing is bringing it
back up to a normal level
My bp still falls if I do too much (41/120) but with 5 minutes of sitting
down it recovers to a normal reading of 65/120.
Even if there is a small risk of problems later on I am prepared to take that
risk to have my life back now. Who knows maybe in another 6 months time when I have chelated more mercury out of my
brain, my adrenals and thyroid might even start to work better and I will
drop my dose to 2.5mg a day..."
|
Pregnenolone
|
Pregnenolone is a steroid hormone involved
in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids,
androgens, and estrogens. As such it is a prohormone.
Pregnenolone (Wikipedia)
|
Since pregnenolone, progesterone, and DHEA are all
biosynthesized from cholesterol by
p450 iron-requiring enzymes, the failure of this enzyme system due to an iron
metabolizing problem caused by hyperimmunity can
lead to low levels of these neuro-hormones.
|
Low levels of these neurosteroids
are known to causebrain fog, especially
pregnenolone.
|
Probiotics
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium longum
Lactobacillus acidophilus
Lactobacillus bulgaricus
Lactobacillus casei
Lactobacillus plantarum
Lactobacillus rhamnosus
Lactobacillus GG
Streptococcus thermoph.
|
Probiotics are dietary supplements containing
potentially beneficial bacteria.
Probiotic bacterial cultures are
intended to assist the body's naturally occurring flora within the digestive
tract to reestablish themselves. They are sometimes recommended by doctors,
and, more frequently, by nutritionists, after a course of antibiotics, or as
part of the treatment for candidiasis. Many probiotics are
present in natural sources such as lactobacillus in yogurt.
Claims are made that probiotics strengthen the immune system.
The rationale for probiotics is that the body contains a miniature ecology of
microbes, collectively known as the gut flora.
The number of bacterial types can be thrown out of balance by a wide range of
circumstances including the use of antibiotics or other drugs, excess
alcohol, stress, disease, exposure to toxic substances, or even the use of
antibacterial soap. In cases like these, the bacteria that work well with our
bodies (see symbiosis) may decrease in number, an event which allows harmful
competitors to thrive, to the detriment of our health.
|
There is no published evidence that probiotic supplements
are able to replace the body’s natural flora when these have been killed off.
There is evidence, however, that probiotics do form beneficial
temporary colonies which may assist the body in the same functions
as the natural flora, while allowing the natural flora time to recover from
depletion.
The probiotic strains are then progressively replaced by a naturally
developed gut flora.
If the conditions which originally caused damage to the natural gut flora
persist, the benefits obtained from probiotic supplements will be short
lived.
The maintenance of a healthy balance of gut flora not only aids digestion
and boosts the immune system but also prevents
constipation, reduces insomnia and is believed to have
beneficial impacts on stress-related illnesses...
|
Prebiotics
Although use of probiotic formulations may well help in achieving these
benefits, it is also possible to increase and maintain a healthy bacterial
gut flora by increasing the amounts of prebiotics in the
diet such as inulin, raw oats, and unrefined
wheat. This is likely to be a more effective mechanism, since without
appropriate food sources in the gut, probiotic organisms will die.
Some products containing probiotic
bacteria include:
- Kefir
- Raw milk
- Yogurt
- Kombucha
- Sauerkraut
- Kimchi
Probiotics (Wikipedia)
|
Procrit
(Erythropoietin)
(Epogen)
(EPO)
(Aranesp)
|
Erythropoietin (EPO) is a glycoprotein hormone that is a
growth factor for erythrocyte (red blood cell) precursors in the bone
marrow.
It increases the number of red blood cells in the blood. Synthetic
erythropoietin is available as a therapeutic agent produced by recombinant
DNA technology. It is used in treating anemia resulting from chronic renal
failure or from chemotherapy for the treatment of cancer. Its use is also
believed to be common as a blood doping agent in endurance sports such as
bicycle racing, triathlons and marathon running.
EPO/Procrit (Wikipedia)
The use of Procrit to treat CFS must be considered experimental, and it is
currently undergoing a 5 year trial at the University of Miami, in Florida,
U.S.A.. One theory is that reduced red blood cell (RBC) mass is a critical
hematological marker of CFS, and that increasing red blood cell production
may result in more energy and reduced fatigue.
|
University of Miami CFS Study:
The Behavioral Medicine Research Center at the University of Miami is conducting
a study funded by the National Heart, Lung, and Blood Institute of the
National Institutes of Health. Dr. Barry Hurwitz Ph.D. and Dr. Nancy Klimas M.D. are the principal investigators of this
study.
CFS Procrit clinical trial phone is
305-575-7154.
The research study is actively searching for CFS patients who would
like to participate in the study.
(11. April 2002)
|
The study is investigating a
potential treatment for Chronic Fatigue Syndrome
(CFS). The study is a placebo-controlled clinical trial in which Procrit is
prescribed to the participants for 13 weeks.
Procrit is a drug that has been used for over a decade to treat anemia which
is low red blood cell volume. The drug increases the production of red blood
cells, which we have discovered is low in many cfs
patients.
Because the red blood cell delivers oxygen to the body, it is projected that
this treatment may reduce the debilitating fatigue experienced by individuals
with cfs.
Other links:
Procrit.com
Ivanhoe.com
|
Propolis
|
Propolis is a wax-like resinous substance collected by
bees from tree buds and used as cement and to seal cracks or open spaces in
the hive. Its color varies from green to brown and reddish, depending of its bothanical source.
Honeybees will use propolis to attempt to seal any gap inside the hive that
is smaller than the bee space, approximately 6.3 mm.
|
Propolis shows powerful local antibiotic and
antifungal properties.
Also it is efficient in treating skin burns. However, research is
inconsistent on its efficacy.
Claims have been made for its use in treating allergy; it
may stimulate the immune system, but some warn that it should not
be taken if the user is likely to have severe allergic reaction to bees.
Propolis (Wikipedia)
|
Increases effects of antibiotics against staph 10 to 100
times. Effective against TB, oral
problems, etc. (?)
|
Q 10, Coenzyme
(Ubiquinone)
(Ubiquinol)
(Ubidecarenone)
(Mitoquinone)
|
Coenzyme Q (CoQ),
also known as ubiquinone or ubiquinol, is a biologically active quinone with
an isoprenoid side chain, related in structure to vitamin K and
vitamin E.
...Because of its ability to transfer electrons and therefore act as
an antioxidant, Coenzyme Q has become a fashionable dietary supplement.
Young people are able to make Q10 from the lower numbered ubiquinones
such as Q6 or Q8. The sick and elderly may not be able to make enough. Q10
thus becomes a vitamin later in life and in illness.
Supplementation of Coenzyme Q10 has been found to have a beneficial effect on
the condition of some sufferers of migraines, and is a common component of
the "mito cocktail" used to
treat mitochondrial disorders and other metabolic disorders.
It is also being investigated as a treatment for cancer, and as relief from
cancer treatment side effects.
|
Recent studies have suggested that Coenzyme Q10 may act as
an important antioxidant in the body and the brain. Some of these studies
have indicated that Coenzyme Q10 may protect the brain from
neurodegenerative disease such as Parkinsons...
Coenzyme 10 (Wikipedia)
Some researchers suggest that
L-carnitine and coenzyme Q10 might have
an additive or synergistic effect.
Both coenzyme Q10 and L-carnitine are involved with maintaining
mitochondrial energy production in cells and may help protect against
oxidative and toxin-induced damage.
|
Boosting energy levels is necessary for people suffering
from CFS. Coenzyme Q10, 100 mg taken 3 times a day, often helps victims of
severe chronic fatigue syndrome.
Coenzyme Q10 has long been prescribed for CFS patients. CoQ10 is a potent
antioxidant that aids in metabolic reactions including the process of forming
ATP, the molecule the body uses for energy. Virtually every cell in the body
contains CoQ10. It is concentrated in the mitochondria, the area of the cells
where energy is produced.
One a study of 20 female patients
with CFS that required bed rest following mild exercise and 20 healthy
controls. Eighty percent of the CFS patients were found to be deficient in
CoQ10 which further decreased following mild exercise or over the course of
normal daytime activity.
After three months of CoQ10 supplementation (100 mg per day) exercise
tolerance (400 kg-meters of work) more than doubled.
All patients had improved. Ninety percent had reduction and/or
disappearance of clinical symptoms, and 85 percent had decreased
post-exercise fatigue.
(Judy 1996) (Werbach 2000)
|
Quercetin
|
Quercetin is a flavonoid that forms the
"backbone" for many other flavonoids, including the citrus
flavonoids rutin, hesperidin, naringin and tangeritin.
Quercetin is found to be the most active of the flavonoids in studies,
and many medicinal plants owe much of their activity to their high quercetin
content.
|
Quercetin has demonstrated significant anti-inflammatory activity
because of direct inhibition of several initial processes of inflammation.
For example, it inhibits both the manufacture and release of histamine and
other allergic/inflammatory mediators. In addition, it exerts potent
antioxidant activity and vitamin C-sparing action.
Quercetin (Wikipedia)
|
Sources:
Coca Leaf, Cauliflower, Catechu, Fishwort, Hops Fruit, Japanese Knotweed,
Neem, Oleander, Prostrate Knotweed, St. John's-wort, Tea Leaf, Tomato,
Woodland Hawthorn, White Mulberry Leaf, Yarrow
Lassesen.com/quercetin
|
Rebirthing
(Breathwork)
(Holotropic Breathing)
(Conscious connected breathing)
(Vivation)
|
Rebirthing is a branch of
alternative medicine which postulates that human birth is a traumatic event
(see birth trauma) and that a discipline consisting of a combination of
connected breathing techniques, relaxation and focused awareness can have
therapeutic benefits.
Rebirthing (Wikipedia)
See
my success with Rebirthing here.
Is Breathwork problem or solution
oriented?
by Wilfried Ehrmann, Ph.D.
(and other interesting articles like
"What is breathwork practice, psychotherapy and spirituality")
|
Disordered Breathing Rhythms
More than half of our patients with FMS or CFS develop a disordered pattern
of breathing. They take very small rapid breaths using the small muscles of
their chest instead of slow, deep breathing with the large muscles of
the abdomen.These changes
are subtle and most people who "hyperventilate" in this manner
don't realize that their breathing pattern is out-of-sync.
Shallow chest breathing makes people feel tense.
Slow, deep abdominal breathing creates feelings of calmness.
Disordered breathing can also cause a broad array of frightening symptoms
including mental fog, dizziness, irritability, chest pain, feeling numb and
more. Worse symptoms then disrupts breathing
further.
Dr. Podell's site
|
...Breath language is especially
rich in communicating emotion. Strong emotions like crying, anger,
fear, sorrow, and pleasure usually involve increased breathing, while
repressing emotions means reducing breathing.
Breath language is a body language. The noises our breath makes such as
puffing, panting, yawning, gasps, snorts, sighs, coughing, choking, and suffocating
are all part of its vocabulary as is the length of the breath and the part of
the body it takes place in. When we are relaxed, we breathe deeply
and slowly into our belly. Stress moves our breath from our belly to our
chest.
Our breath can be a language of illness. When we are ill, our breathing is
affected; when our breathing is inadequate, our health is affected. Hyperventilation
is an indication of stress and anxiety. Hesitation and mental
conflict can trigger asthma attacks...
I-breathe.com
|
Rhodiola Rosea
(Russian Rhodiola)
(Golden Root)
|
Rhodiola rosea is a Siberian herb that is effective for improving
mood and alleviating depression.
Russian research shows that it improves both physical and mental
performance, reduces fatigue, and prevents high altitude
sickness. In one study, the Rhodiola rosea group
decreased proofreading errors by 88% while the control group increased proofreading
errors by 84%.
Rhodiola rosea's effects
are attributed to its ability to optimize serotonin and dopamine levels and
to its influence on opioid peptides such as beta-endorphins.
The stimulant substances involved
are referred to as adaptogens.
Rhodiola Rosea
(Wikipedia)
|
Effects similar to Siberian ginseng.
It's an adrenalin modifier/buffer with antihypoxia
effects, as well as anticoagulant effects. It also increases hemoglobin and
red blood cell levels. (?)
Quality Rhodiola rosea extract should contain at
least 2.5% rosavin and 1% salidroside. (?)
The Russian stuff is considered much better than the Chinese one(?)
|
Sellers:
2ameriden.com/products/rosavinframe.html
Beyond-a-century.com
Naturedistributors.com
Anti-aging-guide.com
Variety of adaptogens including Rosavin:
Cybercities.com/j/jnader/Primeone.html
Dose : 200-300mg per day is safe and effective.
|
Ribose
(D-Ribose)
Beta-D-ribofuranose
Ribose is also sometimes part of the Mito cocktail.
|
Ribose, primarily seen as D-ribose, is an aldopentose - a
monosaccharide...
As a component of the RNA that is
used for genetic transcription, ribose is critical to living creatures. It is
related to deoxyribose, which is a component of DNA.
It is also a component of ATP, NADH,
and several other chemicals that are critical to metabolism.
Ribose (Wikipedia)
The natural dietary supplement
D-ribose - a form of sugar essential to fuel cellular energy generation
- "significantly reduced clinical symptoms in patients suffering
from Fibromyalgia and Chronic Fatigue Syndrome"...
|
How do the researchers think
D-ribose supplementation supports improved CFS and FM patient quality of
life? Many scientists have come to believe that "inefficient" or
"disordered" cellular metabolism may account for the symptoms of
fatigue and muscle pain associated with CFS and FM.
Patients' muscles become "anaerobic" or depleted of oxygen faster
than the muscles of normal healthy people.
And supplementation with the nutrient D-ribose may represent one avenue
for supporting faster regeneration of ATP and healthier metabolism in
oxygen-deprived muscle cells.
Immunesupport.com/ribose (12.Jun.2006)
|
Ribose is used to increase
muscle function, recovery, athletic performance, boost muscle tissue energy,
and enhance effectiveness of creatine, replenish ATP stores,
and improve or maintain nucleotide salvage and/or
synthesis in heart and sceletal muscles following
high intensity exercise...
...Individuals who feel they are overly tired or are concerned about their
energy stores typically take up to 3 grams twice per day or adjust to
perceived benefit.
Naturaldatabase.com
...Ribose and Creatine are
very synergistic (support each other) in their actions...
Bodybuilding.com/store/ribose.html
|
Salt
NaCl
(Hydropulse)
|
Edible salt is a mineral, one of the few rocks humans eat. There are different forms of it:
unrefined salt, refined salt, table salt or iodised
salt. It is a crystalline solid, white, pale pink or light grey in color,
obtained from seawater or from rock deposits. Sea salt comes in fine or
larger crystals. In nature it includes not only sodium chloride, but also
other vital trace minerals. Edible rock salts may be slightly greyish in colour due to this mineral content.
Salt is necessary for the survival
of all living creatures, including humans. Salt is involved in regulating the
water content (fluid balance) of the body. Salt flavor is one of the basic
tastes. Salt cravings may be caused by trace mineral deficiencies as well as
by a deficiency of sodium chloride itself.
Salt is required for life, but overconsumption can increase the risk of
health problems, including high blood pressure, in those individuals who are
genetically predisposed to hypertension. In food preparation, salt is used as
a preservative and as a seasoning.
Edible Salt (Wikipedia)
|
A recent study found an abnormality in blood pressure
regulation in 22 of 23 patients with CFS.
This abnormality, called neurally
mediated hypotension, causes a sudden drop in blood pressure when a
person has been standing, exercising or exposed to heat for a while. When
this occurs, patients feel lightheaded and may faint.
They often are exhausted for hours to days after one of these episodes. When
treated with salt and medications to stabilize blood
pressure, many patients in the study had marked improvements in
their CFS symptoms.
(John Hopkins University)
|
Bacteria don't like salt, so eat
it and gargle with it, and irrigate your sinuses with it.
ENT-consult.com
Salt-Vitamin C theory (Curezone.com)
Salt-n-C (Special CFSFMExperimental-group)
Lyme Strategies (Yahoo-group)
Borreliose-abhilfe (Yahoo-group über Salz und Vitamin C, RIFE, Frequenztherapie)
see also:
Gookinaid
Vitamin C
|
Selegiline
(Selegilin)
|
Selegiline is a Monoamine oxidase B receptor
inhibitor.
Selegiline is sometimes used off-label to treat narcolepsy and
as a nootropic, as well as for its purported life-extending
effects.
It is also reported to positively affect libido, particularly in
older males. As of February 28, 2006, Selegiline has also been approved by
the FDA to treat major depression using a transdermal patch
(Emsam Patch).
Selegiline is also used (at extremely high dosages relative to humans) in
veterinary medicine to treat the symptoms of Cushing's disease and so-called
"cognitive dysfunction" in dogs.
Selegiline (Wikipedia)
|
Selegilin ist ein
Antidepressivum / MAO-Hemmer und bewirkt Verbesserung psychischer Variablen.
uni-züri/klipsy.ch
- Rasagilin gehört
zur Gruppe der selektiven
Monoaminooxidase-Hemmer (MAO-Hemmer) und ist ein MAO-B-Hemmstoff der „zweiten Generation“. Es hemmt
die MAO-B fünf- bis zehnfach
stärker als das bislang aus dieser
Gruppe verfügbare Selegilin.
Rasagilin
(Wikipedia.de)
|
Researchers studied the effect of
Selegiline, a specific monoamine oxidase B receptor inhibitor, against a
placebo in 25 CFS patients over a six-week trial period....
They found that the patients who took Selegiline reported significant
improvement in tension/anxiety, vigor and sexual relations, and that the
drug was not acting as an antidepressant.
PubMed.com (enter
this number in the search field: 98259960 )
|
Serine
(L-Serine)
|
Organic compound, one of the 20 amino acids commonly found
in animal proteins. Only the L-stereoisomer appears in mammalian
protein.
It is not essential to the human diet, since it can be
synthesized in the body from other metabolites, including glycine. Serin was
first obtained from silk protein, a particularly rich source, in 1865.
Serine (Wikipedia)
|
|
ME/CFS patients fulfilling the Fukuda diagnostic criteria
and having low urinary serine excretion were supplemented with 1-3 g L-serine
daily.
Significant reductions in symptom expression were seen in core
CFS diagnostic symptoms, cognitive, neurological and musculoskeletal
symptoms...
Ahmf.org/01emms2.html
|
Sertraline
(Sertralin)
(Zoloft)
(Gladem)
|
Sertraline is used medically mainly to treat the symptoms
of depression and anxiety. It has also been
prescribed for the treatment of obsessive-compulsive disorder,
post-traumatic stress disorder, premenstrual dysphoric disorder, panic
disorder, and bipolar disorder.
Sertraline (Wikipedia)
|
Sertralin ist ein Selektiver Serotonin Wiederaufnahme-hemmer,
der zu einer Erhöhung der Konzentration von
Serotonin im synaptischen
Spalt im Zentralnervensystem
führt.
Nach einer Phase der
Modulation der Serotonin-Rezeptoren kann eine antriebssteigernde und eine
stimmungsaufhellende Wirkung beobachtet werden.
Sertralin
(Wikipedia.de)
|
Sertralin bewirkt eine
Verbesserung der depressiven
Symptomatik. (Ebene III-3)
uni-züri/klipsy.ch
|
Shiitake
Lentinula edodes
|
Mushroom, contains:
- Lentinan
- KS-2 (interferon-inducer)
- 10 % Polysaccharides
Extracts from shiitake mushrooms have also been researched for many other immunological
benefits, ranging from anti-viral properties to possible
treatments for severe allergies.
Lenthionine, a key flavor compound of shiitake,
also inhibits platelet aggregation, so it is a promising
treatment for thrombosis.
Shiitake (Wikipedia)
|
- immune stimulant
- antiviral
- antitumor
Blood samples from cancer patients on KS-2 showed a very definite antiviral
activity, and in mice given KS-2 orally in small doses, blood levels of
interferon increase dramatically.
Interferon is a protein in the human body that interferes directly with viral
replication.
|
Shiitake extract is used in Japan to treat low
natural killer syndrome (LNKS) which is identical to the illness
called chronic fatigue syndrome (cfs) is the US.
In 1985 Dr. Tadao Aoki of the Shinrakuen Hospital in Japan reported that an undisclosed
number of LNKS patients who received lentinan injections (1 mg/day, every
other day) experienced a gradual improvement in "dullness."
In addition, body temperature and natural killer activity gradually returned
to normal.
Complete recovery in the majority of patients occurred within a few months (? ! ?)
Oral dose: 5 mg, which was 5 times the intravenous dose.
Jvm.com
|
Siberian ginseng
(Eleuthero)
Eleutherococcus senticosus
|
Contains:
- Eleutherocide
Attention: Must be standardized for eleutheroside
content!
(According to Dr. Weil)
Siberian ginseng is a powerful tonic herb with an impressive range of health
benefits. Unlike many herbs with a medicinal use, it is more useful for
maintaining good health rather than treating ill health. Research has shown
that it stimulates resistance to stress and so it is now
widely used as a tonic in times of stress and pressure.
In an alarming situation, the adrenal glands release corticosteroids and
adrenaline which prepare the organism for the fight or flight reaction. When
these hormones are depleted, the organism reaches an exhaustive phase. Eleutherococcus delays the exhaustive phase and
allows a more economical and efficient release of these hormones.
Siberian Ginseng (Wikipedia)
|
- increases white blood cells,
- enhances immune system,
- increases energy / recovery,
- normalizes blood pressure
Eleuthero has been reported to increase stamina and endurance and
protect the body systems against stress-induced illness.
It is rumored that Soviet Olympic athletes have used Eleuthero successfully
to enhance sports performance and concentration.
Eleuthero is a different genus than other popular ginsengs such as the
American and Panax or Asian varieties. The use of eleuthero root dates back
2,000 years in the records of Chinese medicine. It was used for respiratory
tract infections, as well as colds and influenza.
|
The Chinese also believed that Eleuthero provided energy
and vitality. In Russia, it was originally used by the Siberian people
to increase physical performance and to increase the quality
of life and decrease infections. Eleuthero has been studied
extensively since the 1940's.
The root has been found to have many adaptogenicbenefits.(11,
12)
- Medon
PJ. 1984
Effects of Eleutherococcus senticosus
extracts on hexobarbital metabolism in vivo and in vitro.
- Davydov M. 2000
Eleutherococcus senticosus
(Rupr. & Maxim.) Maxim. (Araliaceae)
as an adaptogen: a closer look.
- Fulder SJ. 1981
Ginseng and the Hypothalamic-pituitary Control of Stress.
- Asano K, et al. 1986
Effect of Eleutherococcus senticosus
Extract on Human Physical Working Capacity.
|
Spirulina
|
Spirulina is a high protein micro-algae. It's very similar in nutrients to chlorella &
blue algae with even more protein, B12 and
high amounts of phycocyanin.
Beyondacenturyonline.com
|
|
|
Spontaneous healing
(Spontaneous remission)
|
Spontaneous remission is a catch-all expression by the
medical faculty for any healing with no obvious conventional
explanation.
Cases of spontaneous remission are a good example of statistical outliers due
to the large numbers of individuals alive and the corresponding incidences of
disease.
|
Traditional medical practice ascribes the effect to
rationally explainable influences that simply lack observation.
Advocates of faith healing and alternative medicine contend that the expression
is a convenient means for dismissing alternative sources of efficacy.
Spontaneous remission (Wikipedia)
|
Some of the suggested medications
and therapies on this database might even cure the physical causes, especially
the tonics and adaptogens, which I added to this
list after really being inspired by the excellent book Spontaneous Healing, by Dr. Andrew
Weil
See Max Rivers' story on his spontaneous healing from
ME-CFIDS-CFS
|
Staphylococcus toxoid
(Superantigen)
|
Superantigens (SAgs) are a group
of virulent toxins that indiscriminately activate T-cells of the immune
system causing system-wide inflammation and other serious,
potentially fatal symptoms. They are not quite the same as antigens, though
they almost all have antigenic properties, but rather receive their name from
their powers to induce the production of antibodies.
Superantigens are secreted as exotoxins by bacteria, alternatively viruses
hijack our own molecular machinery to generate endotoxin forms of
superantigens. They are mainly associated with species of Streptococcus and
Staphylococcus infections, and are the contributing cause of toxic shock
syndrome. Superantigens are also the suspected cause of numerous diseases
displaying characteristic symptoms with unknown causes.
Superantigen (Wikipedia)
|
Therapie mit Staphylococcus toxoid führt zu einer
Verbesserung von Variablen,
welche die Lebensqualität
betreffen. (Ebene
III-3)
uni-züri/klipsy.ch
|
Clinical global impressions showed
significant improvement in the vaccine-treated group, and VAS did so in both
groups. In a follow-up study of 23 patients, the vaccine treatment was
continued for 2-6 years. Fifty percent were rehabilitated
successfully and resumed half-time or full-time work. The results of
this study support the authors>> hypothesis that treatment with
staphylococcus toxoid may be a fruitful strategy in patients with
fibromyalgia and chronic fatigue syndrome
Pubmed: Effects of staphylococcus toxoid vaccine on pain and
fatigue in patients with fibromyalgia/chronic
fatigue syndrome
|
Suma
Pfaffia paniculata
(Brazilian Ginseng)
(Para toda)
|
Suma , also called Para toda, is the
dried root of Pfaffia paniculata,
a plant found in the Atlantic rain forest of Brazil. First introduced to the
United States as Brazilian Ginseng, Suma is one of the most highly regarded
herbs in South America, and is considered to be a true adaptogen.
|
|
Used by native peoples for centuries, Suma is advocated as
an effective adaptogen to support the immune system, adapt
the body to external stresses, relieve pain, fight chronic
fatigue syndrome, and accelerate wound healing.
Immunesupport.com/glossary
|
Transfer Factor
|
In 1949, H.S. Lawrence discovered
that a part of an individual's white blood cells was responsible for immune
responses while he was studying tuberculosis.
Upon injecting an extract of leukocytes from one host to another, he observed
that these molecules were able to replicate the immune response of the host
to the recipient.
He dubbed these 'immune information' molecules transfer factors for their
ability to "inform" other immune cells regarding their immune
responses to harmful agents.
Transfer factors are found in colostrum of humans and other
animals, most abundantly in cows.
They are made up of amino acids and are antigen-specific, meaning that
specific types of transfer factors can be used to treat specific types of
diseases.
...In an informal study, where extraneous factors were not held constant,
patients who used transfer factor were free from pathogenic disease for the
duration of the administration of transfer factor.
Patients reported spontaneous disappearance of flu and cold symptoms concomitant
with oral administration of transfer factor containing products...
Transfer Factor (Wikipedia)
The immune system's job is to
recognize potentially harmful invaders (pathogens) and then destroy or
neutralize them. Transfer factors are tiny protein molecules which are
produced by immune cells called T-cells. Transfer factors are the key to the
immune system's memory of previous pathogen exposure, and thus, are an
integral component for maintaining immune system integrity and effectiveness.
Transfer factors allow the immune system to remember conditions for which
immunity has already been established. When a person has been infected with
chickenpox in childhood, for example, the body develops a memory of that
illness which prevents the person from becoming re-infected later in life. In
the future, the specific immune transfer factor molecule for chickenpox will
endow the immune system with the exact 'blueprint' of what chickenpox looks
like, and the body will be able to quickly recognize and respond to any
possible re-infection before it can cause disease.
Reportedly the only company that has the patented protected process for
extracting transfer factor is 4LIfe Research.
Apparently many companies are actually using colostrum instead of transfer
factor. (?)
Colostrum contains transfer factors but it is not pure
concentrated transfer factor.
Colostum has all the other properties of the bovine
milk in it, and may cause a reaction.
|
Transferfactor.ws :
Several transfer products have recently been introduced, each with a
different focus or specificity:
ImmuneTransfer C™ and ImmunFactor 2™. These products contain
the widest range of antigen-specific transfer factors in one product. They
are designed for enhanced activity for Human Herpes Virus 6 (HHV-6B),
Epstein-Barr Virus (EBV), Cytomegalovirus (CMV), Chlamydia pneunmoniae, and Borrelia burgdorferi (cell-wall
deficient Lyme), Babesia, and Erlichia. Both
products utilize chicken derived transfer factors with added bovine
colostrum.
Transfer Factor System 200™, Transfer Factor 6000™ and Formula
560™. These products contain enhanced activity for HHV-6, (both A
and B variants), and CMV. Both products are supported by a patent on the
process for obtaining transfer factor from colostrum. Transfer Factor 6000 is
the same high quality patented formula (included in the Hemex™Lab
protocol) as Formula 560, at a lower price.
Transfer Factor System 100™, Transfer Factor 4000™ and Formula
540™. These products contain enhanced activity for Epstein-Barr Virus
(EBV) and CMV. Both products are supported by a patent on the process for
obtaining transfer factor from colostrums. Transfer
Factor 4000 is the same high quality formula as
Formula 540, at a lower price.
Transfer Factor Essentials™ (formerly Transfer Factor
Basics™) This product is a non-antigen specific transfer factor (chicken
derived) product designed for daily use to support any person's immune
system. In addition to transfer factor, it incorporates pretty high levels of
other immune supporting nutrients like beta glucan, IP-6, astragalus, TMG, bovine colostrum, and
larch.
Transfer Factor XF and Transfer Factor Plus. For
individuals seeking only to improve overall immunity without targeting
specific viruses, these products contain only the general transfer factors
found in the colostrum, and do not include transfer factors for any targeted
pathogens such as HHV-6, EBV, CMV etc.
|
Therapie mit TF (transfer factor) führt zu einer
Verbesserung physiologischer
Messwerte (Ebene III-3).
uni-züri/klipsy.ch
Chisolm Labs
4Life Research, Utah (Products
and independent study)
Immunesupport.com (Related
abstracts, and TF-products)
Immunity
Today (TF against HHV-6; variant A&B and EBV)
Dr. Podell's suggestion
on Transfer Factor.
(Based on Dr. Joseph Brewer's double-blind tests)
|
Tropisetron
|
5-HT3 Rezeptorantagonist
5-HT Rezeptoren
(Wikipedia.de)
|
|
Tropisetron bewirkt eine
Verminderung der Erschöpfung
und einen Anstieg der Leistungsfähigkeit (Ebene III-3).
uni-züri/klipsy.ch
|
Turmeric
(Tumeric)
Curcuma longa
|
Turmeric is a spice commonly used in curries and other
South Asian cuisine. Its active ingredient is curcumin. It
is a significant ingredient in most commercial curry powders.
Turmeric is a member of the ginger
family, Zingiberaceae.
In Ayurvedic medicine, turmeric is thought to have many healthful properties.
It is taken in some Asian countries as a dietary supplement, which allegedly
helps with stomach problems and other ailments. It is
popular served as a tea in Okinawa, Japan. It is currently being investigated
for possible benefits in Alzheimer's disease, cancer and liver
disorders.
|
Curcumin, the active ingredient in
turmeric, might inhibit the accumulation of destructive beta amyloids in the
brains of Alzheimer's disease patients and also break up existing plaques.
"Curcumin has been used for thousands of years as a safe anti-inflammatory in
a variety of ailments as part of Indian traditional medicine..."
Turmeric (Wikipedia)
|
Curcuminoid extract from Tumeric is antioxidant (actually prevents formation of
free radicals as well), antiviral, antiinflammatory,
and anticarcinogenic.
Kilohealth.com/curcumin
|
Valganciclovir
(Valcyte)
|
Valganciclovir hydrochloride (Valcyte®) is an antiviral medication
used to treat cytomegalovirus infections.
As the L-valyl ester of ganciclovir, it is actually a prodrug for
ganciclovir. After oral administration, it is rapidly converted to
ganciclovir by intestinal and hepatic esterases.
Valganciclovir (Wikipedia)
Valganciclovir is a prescription drug approved for treating HHV-6 infections
of the eye, which can occur in individuals with severely weakened immune
systems, such as transplant or cancer patients. The HHV-6 virus is not the
same as the herpes simplex virus that causes cold sores. Most commonly, it is
associated with a condition called roseola infantum, a fever and a rash in
children.
|
Professor Montoya:
"...Donna was sent to me because high levels of another virus (Epstein
Barr)had
been detected in her system. I found high levels of HHV-6 virus as
well, so I treated her with valganciclovir to bring down her viral load. I'd
hoped it might help a bit, but I didn't expect the results to be anything so
dramatic. It was pure serendipity..."
"...It can have serious
side-effects including anemia, so you have to monitor patients very
carefully. But so far none of the CFS/ ME patients have reacted badly to
it..."
|
Participants report: “Soaring energy levels”
“When Donna came to see us, her
energy levels were around 10 per cent of what she considered normal,”
Professor Montoya was quoted as saying. “Today, she is functioning at 90 per
cent.”
A patient who could hardly walk all the way around the block is now bicycling
for up to three hours each day.
Another patient who could not even leave the bed now comes to breakfast every
day at 7:00 AM.
Immunesupport.com/valganciclovir
|
Vitamin A
(Retinol)
(Axerophthol)
|
Retinol, the dietary form of
vitamin A, is a fat-soluble, antioxidant vitamin important
in vision and bone growth.
It belongs to the family of chemical compounds known as retinoids.
Retinol is ingested in a precursor form; animal sources (milk and eggs)
contain retinyl esters, whereas plants (carrots, spinach) contain pro-vitamin
A carotenoids.
... Vitamin A is essential to provide intact epithelial tissues as a physical
barrier to infection; it is also involved in maintaining healthy
lymphocytes and T-cells.
...Vitamin A affects the production of human growth hormone.
Vitamin A (Wikipedia)
|
|
Vitamin A plays a role in the development of
T-helper and B cells. Vitamin A deficiency impairs innate immunity by
diminishing the function of neutrophils, macrophages, and natural killer
cells.
Although vitamin A does play a
role in balancing Th1 and Th2 function, it does so by downregulating Th1 cell
IFN-gamma
secretion directly, decreasing activated antigen presenting cell (APC)
function, and promoting Th2 cell growth and/or differentiation. Therefore,
although vitamin A is an important nutrient for immune function, cfs-patients should avoid excessively high doses.
(Wiedermann, Hanson et al. 1993)
(Cantorna, Nashold et al.
1994)
(Cantorna, Nashold et al.
1995)
(Watzl, Bub et al. 1999)
(Stephensen 2001)
|
Vitamin B
|
B1 Thiamine
B2 Riboflavin
B3 Niacin (also Vitamin P or Vitamin PP)
B5 Pantothenic acid
B6 Pyridoxine and Pyridoxamine
B7 Biotin (also Vitamin H and Vitamin B-w )
B9 Folic acid (also Vitamin M and Vitamin B-c, important
for pregnancies)
B12 Cyanocobalamin
|
...The B vitamins often work together to deliver a number
of health benefits to the body. B vitamins have been shown to:
- Bolster metabolism
- Maintain healthy skin and muscle tone
- Enhance immune and nervous system function
- Promote cell growth and division
- Together, they also help combat the symptoms and causes of stress,
depression, and cardiovascular disease.
|
All B vitamins are water soluble, and are dispersed throughout the body and must be
replenished daily with any excess excreted in the urine.
Vitamin B comes from a number of natural sources, including potatoes,
bananas, cereal, lentils, liver, turkey, and tuna. Brewer's yeast is an especially
good source of Vitamin B.
Vitamin B (Wikipedia)
|
Vitamin C
Ascorbic acid
|
Vitamin C is a water-soluble nutrient and
vitamin essential for life and for maintaining optimal health. It is also
known by its chemical name ascorbic acid. It is used by the body for many
purposes.
As a participant in hydroxylation, vitamin C is needed for the production of
collagen in the connective tissue. These fibers are ubiquitous throughout the
body, providing firm but flexible structure. Some tissues have a greater
percentage of collagen, especially: skin, mucous membranes, teeth and bones.
|
Vitamin C is required for synthesis of dopamine,
noradrenaline and adrenaline in the nervous system or in the adrenal glands.
Vitamin C is also needed to synthesize carnitine,
important in the transfer of energy to the cell mitochondria.
The tissues with greatest percentage of vitamin C — over 100 times the level
in blood plasma — are the adrenal glands, pituitary, thymus, corpus luteum,
and retina.
The brain, spleen, lung, testicle, lymph nodes, liver, thyroid, small
intestinal mucosa, leukocytes, pancreas, kidney and salivary glands usually
have 10 to 50 times the concentration present in plasma.
Vitamin C is an antioxidant.
Vitamin C (Wikipedia)
|
One study showed the value
of DHEA and
vitamin C infusion treatment in the control of cfs.
Salt-Vitamin C theory (Curezone.com)
Salt-n-C (Special CFSFMExperimental-group)
Lyme Strategies (Yahoo-group)
Borreliose-abhilfe (Diskussionsforum
über Salz und Vitamin C,
RIFE, Frequenztherapie)
|
Vitamin D
|
Vitamin D1:
molecular compound of ergocalciferol with lumisterol, 1:1
Vitamin D2: ergocalciferol or calciferol
Vitamin D3: cholecalciferol
Vitamin D4: 22,23-dihydroergocalciferol
Vitamin D5: sitocalciferol
Vitamin D plays an important role in the maintenance of an intact and strong
skeleton. Its primary task is to regulate the amount of calcium and
phosphorus in the blood by ensuring correct intake and secretion
(from intestines and urine, respectively).
Several studies show that vitamin
D also regulates the growth of skin cells. Psoriasis gives
shell-like skin as a result of uncontrolled cell growth. A vitamin D compound
is used in the treatment of this disease.
The human body produces its own vitamin D in the skin. This process is
dependent on ultraviolet radiation from sunlight. However, Vitamin D
should not be excluded from the diet – this is especially important for
people who do not receive sufficient sunlight.
|
...Those who avoid or are not exposed to summer midday
sunshine may also require Vitamin D supplements. In particular,
recent studies have shown Australians and New Zealanders are Vitamin D
deficient...
...In practice, the human body has enormous storage capacity for vitamin D,
and in any case all common foods and correctly-formulated vitamin pills
contain far too little for overdose to ever occur in normal circumstances and
normal doses...
...The exact long-term safe dose is not entirely known, but intakes of up to
2000 IU (10x the RDA) are believed to be safe, and some researchers believe
that 10,000 IU does not lead to long term overdose...
Vitamin D (Wikipedia)
|
"Since I started taking vitamin D and magnesium, the
sciatica has completely gone.
The brain-fog is almost gone. The prostate problems and sleepiness are
greatly improved.
My dentist tells me that the health of my teeth and gums has improved
dramatically. The skin sores, reflux and the mucous in the stool have shown
some improvement."
Cfs-recovery.org/vitamin_d_recovery
CFSProtocol · CFS Zero Based
Protocol (Yahoo-group)
"For what it's worth"-protocol
(Ken Lassesen)
Vitamin D (Ken Lassesen)
|
Xylitol
(Wood sugar)
(Birch sugar)
|
Xylitol, also called wood sugar or birch
sugar, is a five-carbon sugar alcohol that is used as a sugar substitute.
It can be extracted from birch, raspberries, plums, and corn and is primarily
produced in China.
Xylitol, gram for gram, is roughly
as sweet as sucrose, but contains 40% less food energy.
Xylitol (Wikipedia)
Non-insulin producing sugar-alcohol looks and tastes like sucrose but a bit
sweeter and “cooler” in the mouth.
Found in many fruits & vegetables, it is produced from birch wood or corn
cobs.
Has anabolic, anticatabolic and immunestimulating effects, and fights
fatigue from strenuous aerobic and anaerobic activities with its antioxidant
and ATP increasing properties.
|
Studies show it inhibits
bacteria that cause dental caries, plaque, mouth sores & ear
infections by coating the bacteria so that they are less likely to
adhere to cells.
Children taking 8g/day had 40% fewer ear infections. A 5%
solution in saline is sold as a nasal spray. Use with green tea for a
mouthwash you can drink. Builds stronger bones and tooth
enamel.
With only 2.4 Calories per gram (40% fewer than sugar) and a glycemic index
of 7, it maintains a steady low level of blood sugar and insulin.
Beyond-a-Century.com
|
Nasal-Xylitol.com
(This site provides information on xylitol and why a nasal spray
with xylitol works as well as it does to clean the nose and eliminate the
problems that frequently originate there.)
(For a mouth rinse you can swallow,
use Green Tea!)
Xylitol
toothpaste:
Lef.org/pages/tooth
|
Zadaxin
Thymalfasin
Thymosin alpha 1
|
Immune
modulator
Article from Immunesupport.com/4633 :
...Based on the postulates of viral and autoimmune etiologies of cfs,
several interventions have been designed and tested by different research
groups around the world, including the United
States, Sweden, United Kingdom, Italy, and Japan.
This review addresses those interventions aimed at altering the balance of
certain cytokines, the mediators of immune responses.
Cfs-patients who show evidence of activation of the
immune system
have poor immune cell function and a predominance of what is called a
T-helper (Th)2-type cytokine response when their lymphocytes are activated.
A Th2-type response, which is characterized by production of cytokines such
as interleukin (IL)-4, -5, and -10, favors the function of B lymphocytes, the
cellular factories of immunoglobulins.
Another article from
Immunesupport.com/4181 :
...A predominance of a Th2-type response is therefore consistent with
pathologies, such as autoimmunity and atopy, which are based on inappropriate
production of immunoglobulins.
Many of the cfs therapies discussed decrease the
Th2-type predominance seen at baseline in cfs-patients,
thereby allowing a greater predominance of a Th1-type response, which favors
the function of macrophages
and natural killer cells.
The function of the latter cells, which have the natural ability of directly
destroying invading microbes and cancer cells, is defective in untreated CFS
patients.
Typical Th1-type cytokines include IL-2
and interferon-gamma, and some of the therapies induce their production.
|
SciClone Pharmaceuticals in San Mateo, California, Sciclone.com produces
Zadaxin which is a subcutaneously administered,
synthetic preparation of a natural peptide, thymosin alpha 1, which among
other positive actions enhances the body's Th1 immune response to viral
infections (current clinical studies target hepatitis C and hepatitis B) and
to certain cancers (current clinical studies target malignant melanoma and
hepatocellular carcinoma).
Zadaxin promotes stem cell differentiation into
helper T-cells and differentiation of those cells into the Th1 subset
by increasing the production of cytokines such as IL-2 and gamma
interferon and decreasing production of IL-4.
In addition, studies suggest that Zadaxin
also increases the number and function of cytotoxic T-cells and natural
killer cells.
...Thus, compounds which drive the immune response toward a Th1
profile could be highly effective in fighting chronic viral infection.
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As the name "thymalfasin" suggests this drug is the peptide
originally isolated from the thymus gland and tested on animals after the
thymus gland was removed to reconstitute the immune system.
A healthy functioning thymus is essential to a healthy immune system.
Alternative medicine and anti-aging physicians have been prescribing thymus
extract for some time.
But this peptide is not readily absorbed through the gut, and there are some
safely risks to the use of animal glandulars.
Zadaxin, is a synthetic peptide which exactly
matches the human thymosin alpha 1 peptide. It is taken by injection and has
none of the risks of an animal product.
... Zadaxin is indicated in infections that shift
the immune system to Th 2 when a Th 1 response is needed. Patients with cfs, fibromyalgia, and gulf war illness seem to have an
immune system shifted toward Th 2 immunity.
… Zadaxin should be useful in any disease where the
immune system needs to be shifted toward Th 1 immunity.
...Some of these reasons include infections such as viruses and certain
bacteria which are intracellular such as:
- Chlamydia,
- rickettsia ,
- mycoplasma,
- and post Q fever syndrome.
A combination protocol similar to the one being used in phase 3 trials for
hepatitis C would include either antivirals or antibiotics in combination
with two injections of Zadaxin per week for six
months to a year.
This is not currently being tested, therefore a
patient would need to assume responsibility for this treatment including the
cost of purchasing Zadaxin in another country.
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