Aloe Juices, Gels, and Supplements Review

How Much Aloe is Really in Aloe Products? Find Out and See Our Top Picks.

Medically reviewed and edited by Tod Cooperman, M.D. Tod Cooperman, M.D.

Initially Posted: 11/22/2021

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Table of Contents

Summary

·         Be very careful when you select and use an aloe product! Aloe products differ by the type of aloe, part of the aloe leaf used, and amount of purification (See "What It Is"). What's more, ConsumerLab.com has found that many products over the years don't contain their expected amounts of key aloe compounds (See "What CL Found")

·         Aloe vera "gel" and aloe vera "juice" that has been purified (or "filtered"), are the safest forms of aloe and are often applied to the skin or consumed as a liquid in small amounts for potential therapeutic purposes (See "What It Does").

·         Whole aloe vera leaf (as well as Aloe ferox leaf) contains aloe "latex" (known as aloins) which, if consumed, can cause a significant laxative effect (See "What It Does"). These compounds have also been shown to cause cancer in some animals (See "Concerns and Cautions"). The FDA has banned the sale of all aloe products as over-the-counter (OTC) medicine, although they remain legal as dietary supplements. Also be aware that some aloe gels and sprays have been found to contain benzene, a carcinogen.

·         See our Top Picks among drinkable aloe, topical aloe, and aloe capsules based on our tests and comparisons.

What It Is:

Aloe vera (typically labeled as Aloe barbadensis) is a short-stemmed cactus-like plant with thick and fleshy leaves. The inner part of the leaf contains aloe "gel" which, although mostly water, includes polysaccharide compounds, including acemannan.

The outer portion of the leaf, beneath the skin, contains a different array of compounds including aloins (one of which is the compound emodin), or aloe "latex." Products made of whole aloe leaf or unpurified aloe leaf juice will contain these compounds. Filtration and other purification processes can reduce the amount of latex from aloe leaf juice. This purification is sometimes referred to as "decolorization" as it removes the yellowish latex. Products made of purified aloe vera leaf, or of aloe vera gel (described above), will contain very little latex. While most aloe products are made with Aloe barbadensis, be aware that other species may be used, such as Aloe ferox (also called Cape aloe), which contains more latex, although this should be noted on the label.

What It Does:

Oral use:
Aloe vera juice (containing latex) can relieve constipation due to its action as a stimulant laxative (see Concerns and Cautions).

There is some preliminary, but insufficient evidence for the use of aloe for ulcerative colitis (100 ml aloe vera gel twice daily for 4 weeks) (Langmead, Aliment Pharmacol Ther 2004) and diarrhea-predominant irritable bowel syndrome (IBS) (50 ml decolorized aloe leaf extract taken four times daily for one month) (Davis, Int J Clin Pract 2006). Preliminary evidence suggests that oral administration of aloe vera gel might be effective in reducing blood glucose in patients with type 2 diabetes and in lowering elevated blood lipid levels. Taking aloe orally has also been proposed as a treatment for osteoarthritis, due to aloe's potential anti-inflammatory action (Cowan, BR J Community Nurs 2010). However, there have been no large, long-term, randomized, controlled clinical studies with aloe gel for these uses.

Topical use:
Although aloe vera gel is often used after sunburn or other burns, the evidence is mixed as to whether it helps. It has also been applied to the skin of patients receiving radiation therapy, but has not been effective in reducing redness, itching, or peeling.

Some preliminary evidence suggests that a cream made with 0.5% aloe (as opposed to pure aloe gel) may be effective for treating genital herpes lesions. There is mixed evidence for this cream in treating psoriasis. Several studies have evaluated topical aloe in wound healing and, again, the results have been mixed; in fact, one study suggested that aloe can actually impair wound healing.

An ointment made of aloe may reduce symptoms of seborrhea (red, scaly skin eruptions), and some studies have shown benefits using aloe gel to relieve symptoms of lichen planus, a skin condition characterized by itchy, flat, scaly patches.

Placing aloe in the eye is recommended on some websites as a "home remedy" for dry eye. This, however, appears to be based solely on a laboratory study on cells from the cornea of the eye which found that certain ethanol and ethyl acetate extracts of aloe reduced markers of inflammation and had free radical scavenging effects (Wozniak, Pharm Biol 2012). Animal studies in which aloe has been used to treat corneal lesions and burns have yielded mixed results (Green, J Toxicol Cutaneous Ocul Toxicol 2008Atiba, Clin Ophthalmol 2015).

Quality Concerns and Tests Performed:

Neither the Food and Drug Administration (FDA) nor any other federal or state agency routinely tests supplements for quality prior to sale. In order to help consumers identify products of better quality, ConsumerLab.com purchased and tested aloe supplements, gels, and liquids to determine whether they contained the labeled and expected amounts of acemannan (expected to be 5% of the dry weight of aloe vera gels and aloe vera 200:1 extracts, and 2.5% of the dry weight of aloe vera leaf juice), as well as aloins and emodin, which should only be found in appreciable amounts in products made from the whole aloe leaf or its juice or products listing Aloe ferox, Cape aloe, or aloe latex. Products were also tested for potential contamination with lead, cadmium, and arsenic. See How Products Were Evaluated for more information on testing.

What CL Found:

Here's the run-down of what we found among the products, none of which was found to be contaminated with heavy metals (lead, cadmium, or arsenic).

How Much Aloe Is in "Aloe" Products?

Products containing aloe should contain the key aloe compound acemannan. Shown below are the amounts of acemannan in 2 fl oz (1/4 cup) of drinkable products, one ml (1/5 teaspoon) of topical gels and sprays, or one capsule of an aloe supplement.

Among drinkable aloe products, similar amounts of acemannan per 2 fl oz were found in three products, Lakewood (32.2 mg), Lily of the Desert (38.6 mg), and AloeCure (42.5 mg), while less than half this amount was found in Solaray Aloe Vera Drink (note that the term "drink" means that a product may contain substantial amounts of other ingredients). However, no acemannan could be detected in George's 100% Aloe Vera. It was, essentially, distilled water. In fact, no other compounds that help identify authentic aloe (which include glucose and malic acid) were detected in George's.

Although the label on George's proclaims it to be "100% ALOE VERA" it also notes, in smaller font, that it is a "Fractionally Distilled Liquid from Aloe Vera Leaves," so it is possible that it was made from aloe (which, like many plants, is 99% water), but the key aloe compounds were removed by distillation. George's would not be expected to provide any of the health benefits associated with aloe (other than hydration from water). Why would a product that is essentially water be marketed as an aloe product? Aloe gel and juice tends to have a bitter or sour taste, so removing natural compounds and focusing on the water content makes for a more palatable drink -- in fact, many online reviews rave that George's tastes "just like water." It may be the most expensive water you can buy!

[Be aware that our tests of aloe in 2015 found that Carlson Aloe Vera Gel (sold as softgels) also had no detectable acemannan, and Aloe Farms Aloe Vera Gel (sold in a large bottle) was highly diluted (just 6.6 mg of acemannan per 2 fl oz). In addition, Alo Exposed Original + Honey, which claimed to contain "15% Juice" (i.e., aloe vera juice), had only trace amounts of acemannan, suggesting little to no aloe vera juice. However, Pharm-Aloe Freeze Dried Aloe Vera Leaf Juice (tested in 2017) provided 47.4 mg of acemannan per capsule. Lakewood Organic Pure Aloe Gel had a high concentration of acemannan — 50 mg per 2 fl oz — but this is a different product than the Lakewood Organic Pure Aloe tested this year, which is aloe vera "juice" and not "gel" and contained a lower but still substantial amount of acemannan (32.2 mg per 2 fl oz, or 128.9 mg in a full cup).]

Among topical productsAubrey Aloe Vera had triple the concentration of acemannan as Lilly of the Desert 99% Aloe Vera Gelly and nearly five times the concentration in Burn Out Aloe Vera Skin Fix. In fact, per milliliter, the amount of acemannan in Aubrey (0.7 mg/mL) is essentially the same or more than in most of the drinkable aloe juices (mg/mL values are shown in the 2nd column of the Results table below). Interestingly, the other two topical products are much more viscous (gel-like) than Aubrey, but that's because they contain added thickeners. In fact, thickeners are the second listed ingredient in both of those products: "ammonium polyacryloyldimethyl taurate" in Lily of the Desert and "carboxymethyl cellulose" in Burn OutAubrey's label notes that it has "no artificial thickeners."

It's worth noting that in our tests of aloe in 2015, Fruit of the Earth Aloe Vera 100% Gel had no detectable acemannan. Its "gel" feel was due to "carbomer," a gel-forming polymer made from acrylic acid. We found that when the gel dried, it was nearly impossible to remove from objects. In fact, a CL member who had used it on her hair reported that, after it dried, it would not come out and she had to cut off her matted hair to get rid of it.

The supplements that we tested are specifically used as laxatives and contain little acemannan, but were rich in aloe latex (aloins). Priority One had higher amounts of aloins as well as more acemannan than Nature's Way.

Acemannan Found in Aloe Products (In Milligrams Per Serving)

Cost
The cost to get aloe (based on amounts of acemannan in products and the price of the products) is shown below. The least expensive source is, by far, Lily of the Desert Aloe Vera Juice, as 20 cents per 25 mg (in about 1.5 fl oz). The cost of Lakewood is almost double, Aloe Cure is four times as expensive, and Solaray is almost 15 times as much.

Among the topical productsAubrey Organics was by far the least expensive way to get aloe, costing just one-quarter as much as Burn Out and one-ninth that of Lily of the Desert.

Among the supplements, although Priority One contained about twice the amount of acemannan as well as aloins as Nature's Way (as shown above) per capsule, it was also much more expensive at 36 cents versus 5 cents per capsule. Consequently, Nature's Way was actually a less expensive source of these compounds than Priority One, as shown below.

Cost to Get 25 mg of Acemannan from Aloe Products

Top Picks:

Below are ConsumerLab's Top Picks, based on quality and cost, among aloe products tested and Approved in this review:

Drinkable Aloe:
Lily of the Desert Aloe Vera Juice is our Top Pick in this category as it contains more acemannan and at lower cost (20 cents per 25 mg of acemannan) than the other drinkable aloe products. Like all of the drinkable aloes that we tested, this product has no detectable aloins, so should not have a laxative effect. This product was also our top choice in this category in 2015 when the label design was different but the listed ingredients were the same, although it actually provided a higher amount of acemannan (45.1 mg) than now (38.6 mg) per 2 fl oz. 

While Lily of the Desert Aloe Vera Juice is our Top Pick, we can't say that it or any of the Approved, drinkable products taste good -- all are sour. They each include contain citric acid or lemon juice (as source of citric acid) to help avoid browning, stabilize the juice, and overcome aloe's natural bitterness), but Lily of the Desert stood out as the best-priced, high-quality drinkable aloe.

Topical Aloe: (Gels and Spays)
Aubrey Aloe Vera is our Top Pick in this category. A similar product from Aubrey was our top choice in 2015. Although it doesn't have the gel-feel of the other two topicals, it contains much more aloe and the "gel" feel of the others is largely due the addition of thickeners, as noted earlier. Aubrey has no artificial thickeners, just aloe leaf juice and preservative/moisturizer made from fermented radish root. It is also a less expensive source of aloe than the others. An 8 fl oz bottle costs $10.49. (It is a pump spray, so contains no propellants.)

Aloe Latex Capsules:
Aloe latex is potentially dangerous due to its laxative and potential cancer-causing effects (see Concerns and Cautions), and the FDA no longer allows it be sold as an over-the-counter drug — although it can be sold as a dietary supplement. Consequently, we have no Top Pick in this category. Both products, however, contained the aloin (latex) expected in authentic Aloe ferox and are, therefore, Approved. Priority One Aloe Complex is more potent -- a capsule contained more than twice the amount of aloins than found in Nature's Way. If you are going to use one of these products, we would suggest first trying Nature's Way. It is worth noting that, when we tested a similar Nature's Way product (Nature's Way Aloe Latex & Leaf) in 2015, it had only half the amount of aloins (5.6 mg) and emodin (36.7 mcg) per capsule than the product we tested this year. 

Test Results by Product:

Listed below are the test results for 10 aloe products selected by ConsumerLab.com. The products are listed alphabetically within their category of product.

Also shown are the labeled amounts and types of aloe ingredient, listed serving sizes, amounts of acemannan expected and/or found, and findings for aloins, emodin, and heavy metals. Products listed as "Approved" contained their claimed and/or expected amounts of acemannan and met ConsumerLab.com's other criteria for quality (see Passing Score). Price and cost comparisons are in the 4th column, notable features are in the 5th column, and the full list of ingredients is the final column on the right.

Columns can be swiped left and right

Results of ConsumerLab.com Testing of Aloe Drinks, Topicals and Supplement

(Click arrows or swipe left or right to see all columns)

Approval Status

Product Name

Claimed Amount of Aloe

Acemannan Found

Aloins/Emodin

Heavy Metals

Pill Size

Suggested Serving on Label

Impression

Cost for Suggested Serving

[Price per 25 mg of Acemannan]

Price

Notable Features

Full List of Ingredients Per Serving

Drinkable Aloe Vera Gel or Filtered Juice:

APPROVED

AloeCure® Pure Aloe Extract - Grape Flavor

Click to View Large Photo

Dist. by American Global Health Group, LLC

2 fl oz [60 ml] (1/4 cup)

60.4 g [2 oz] fresh aloe leaves inner gel extract

Expecting 15 mg acemannan

Found:
Acemannan: 42.5 mg

(709 mg per L)

Aloins A and B: Undetectable 

Emodin: Undetectable 

Heavy Metals: NA

Drink 60 ml, the equivalent of 4 tablespoons (2 fl oz), twice per day.

Cloudy, light yellow, slightly viscous liquid. Somewhat sour with slight grape flavor.

$1.40/2 fl oz

[$0.82]

$69.95/six 16.7 fl oz [500 ml] plastic bottle (approx. 48 total servings)

Stevia extract 6 mg per 2 fl oz

No sugar added.

2 fl oz
Calories 0, Calcium 40 mg, Sodium 20 mg, Potassium 21 mg, Aloe Vera Extract (Made from fresh aloe leaves inner gel) 2 oz, Stevia extract 6 mg.

Ingredients: Organic Aloe Vera extract, honey, citric acid, xanthan gum, Sodium Benzoate (preservative), stevia extract, grape flavor. Processed with pure water. Contains 98.7% Pure Organic Aloe Vera Extract by Volume.

NOT APPROVED

George's 100% Aloe Vera

Click to View Large Photo

Dist. by Warren Laboratories, LLC

8 fl oz [240 ml] (1 cup)

Conflicting claims: labeled as "100% aloe vera" but then claims to be a "distilled liquid" from aloe vera

Expecting 59.5 mg acemannan if "100% aloe vera juice"

Found:
Acemannan
Undetectable
(No aloe vera detected in product)

Heavy Metals: NA

No directions listed

Clear liquid with taste of clean water.

$3.19/8 fl oz

[Infinite cost, as no acemannan found]

$3.19/8 fl oz [240 ml] plastic bottle (1 serving)

Bitter Free - No Unpleasant Taste. No Preservatives. No Additives. Anthraquinone Free.

8 fl oz
Calories 10, Total Fat 0 g, Saturated Fat 0 g, Trans Fat 0 g, Cholesterol 0 mg, Sodium 5 mg, Total Carbohydrate 2 g, Dietary Fiber 0 g, Total Sugars [Includes 0 g Added Sugars] 0 g, Protein 0 g, Vitamin D 0 mcg, Calcium 0 mg, Iron 0 mg, Potassium 0 mg.

Ingredients: Fractionally Distilled Liquid from Aloe Vera Leaves.

APPROVED

Lakewood® Organic Pure Aloe

Click to View Large Photo

Dist. by Lakewood®

8 fl oz [240 ml] (1 cup)

99+% aloe vera juice

Expecting 60.5 mg acemannan

Found:
Acemannan: 128.9 mg

(537 mg per L)

Heavy Metals: Pass

No directions listed

Clear liquid. Slightly sour.

$1.90/8 fl oz

[$0.37]

$7.49/32 fl oz [946 ml] plastic bottle (approx. 4 serving)

USDA Organic seal. Kosher. Organic. Non-GMO. BPA/ BPS/ DEHP Free. Unsweetened. No Preservatives. Gluten Free. Allergen Free. Casein Free. Latex & Aloin Free (contains less than 2 ppm aloin). Not From Concentrate / No Added Citric Acid. Fresh Pressed®.

8 fl oz
Calories 10, Total Fat 0 g, Saturated Fat 0 g, Trans Fat 0 g, Cholesterol 0 mg, Sodium 200 mg, Total Carbohydrate 2 g, Dietary Fiber 1 g, Total Sugars [Includes 0 g of Added Sugars] 0 g, Protein 0 g, Vitamin D 0 mcg, Calcium 200 mg, Iron 0.4 mg, Potassium 940 mg, Magnesium 60 mg, Manganese 1.1 mg.

Ingredients: Organic Aloe Vera Juice, less than 1% Organic Lemon Juice.

APPROVED

Top Pick

for drinkable aloe

Lily of the Desert® Aloe Vera Juice

Click to View Large Photo

Dist. by Lily of the Desert

$ Price Check

2 fl oz [59 ml] (1/4 cup)

58.2 g [58 ml] organic aloe fillet juice

60 mg organic polysaccharide rich Aloesorb

Expecting 14.6 mg acemannan

Found:
Acemannan: 38.6 mg

(654 mg per L)

Aloins A and B: Undetectable 

Emodin: Undetectable 

Heavy Metals: NA

Drink 1-2 oz. per serving, up to 8 oz. daily.

Slightly cloudy liquid. Sour.

$0.30/2 fl oz

[$0.20]

$4.89/32 fl oz [946 ml] plastic bottle (approx. 16 serving)

Calcium 25 mg & magnesium 4 mg per 2 fl oz

USDA Organic seal. OneCert® Certified Organic seal. Certified Aloe & Content & Purity In This Product International Aloe Science Council seal. Kosher. Aloin free (less than 1 ppm). Allergen free (allergen free facility). BPA free. Naturally gluten free. GMO free. Vegan. Non-GMO.

2 fl oz
Calories 4, Sodium 12 mg, Total Carbohydrates 1 g, Calcium 25 mg, Magnesium 4 mg, Certified Organic Aloe Vera fillet Juice 58 ml, Certified Organic Polysaccharide Rich Aloesorb™ 60 mg.

Other Ingredients: Organic Lemon Juice Concentrate (pH stabilizer). Contains over 99% organic aloe vera juice.

APPROVED

Solaray® Super Digestaway™ Aloe Vera Gel Drink

Click to View Large Photo

Mfd. by Nutraceutical Corp.

2 fl oz [57 g] (1/4 cup)

No amount listed of aloe inner gel fillet

Expecting 14.5 mg acemannan

Found:
Acemannan: 13.4 mg

(226 mg per L)

Heavy Metals: Pass

Drink 2 oz. (4 Tbsp.) of Super Digestaway™ Aloe Vera up to three times daily.

Faint yellow, very slightly cloudy liquid. Sweet and sour taste.

$1.57/2 oz

[$2.94]

$25.18/32 fl oz [912 g] plastic bottle (approx. 16 serving)

Solaray Guarantees that NO ingredients other than those listed on this label have been added to this product.

2 oz
Calories 10, Total Fat 0 g, Total Carbohydrate 2 g, Sugars 2 g, Protein 0 g, Sodium 5 mg.

Other Ingredients: Pure Deionized Water, Aloe Vera Inner Gel Fillet, Crystalline Fructose, Natural Vanilla Flavor, FOS (Fructooligo-saccharides), Herbal Blend (chamomile [flowering tops], slipper elm [bark], peppermint [aerial], marshmallow root, blessed thistle [seed], and ginger root), Sorbic Acid (to protect flavor) and Citric Acid (pH Adjustor).

Topical Aloe Vera:

APPROVED

Top Pick

for topical aloe (gels and sprays)

Aubrey® Aloe Vera

Click to View Large Photo

Dist. by Aubrey Organics, Inc.

$ Price Check

Spray with no specific serving size

Per 1 ml:

Aloe leaf juice is the first of two listed ingredients, but specific amount not stated

Expecting 0.25 mg acemannan

Found:
Acemannan: 0.76 mg

Heavy Metals: NA

Spray onto affected areas of the skin as needed.

Spray liquid with no fragrance.

$0.04/ml

[$1.45]

$10.49/8 fl oz [237 ml] plastic bottle

Contains leuconostoc/ radish root ferment filtrate

Made with IASC Ingredients. Not from Concentrate.

Ingredients: Aloe barbadensis (aloe) leaf juice, leuconostoc/ radish root ferment filtrate.

APPROVED

Burn Out Aloe Vera Skin Fix

Click to View Large Photo

Dist. by Sun Research LLC

Gel with no specific serving size

Per 1 ml:

Aloe leaf juice is the first of many ingredients, but specific amount not stated

Expecting 0.022 mg acemannan

Found:
Acemannan: 0.16 mg

Heavy Metals: NA

Apply generously morning and night on all areas needing hydration.

Pump gel with light fragrance.

$0.04/ml

[$6.28]

$14.00/12 fl. oz plastic bottle

Contains organic matricaria flower extract, organic Calendula officinalis flower extract, organic lavender flower extract, organic white tea extract, organic cucumber extract, organic Arnica montana flower extract

Petroleum-free, Paraben-free, Fragrance-free.

Ingredients: Organic Aloe Barbadensis Leaf Juice, Carboxymethyl Cellulose, Magnesium Ascorbyl Phosphate, Organic Chamomilla Recutita (Matricaria) Flower Extract, Organic Calendula Officinalis Flower Extract, Organic Lavandula Angustifolia (Lavender) Flower Extract, Organic Camellia Sinensis (White Tea) Extract, Organic Cucumis Sativus (Cucumber) Extract, Organic Arnica Montana Flower Extract, Mixed Tocopherols, Phytoplankton, Ascorbic Acid, Ethylhexylglycerin

APPROVED

Lily of the Desert 99% Aloe Vera Gelly

Click to View Large Photo

Mfd. by Lily of the Desert

$ Price Check

Gel with no specific serving size

Per 1 ml:

99% aloe vera juice gelly
Expecting 0.25 mg acemannan

Found:
Acemannan: 0.22 mg

Heavy Metals: NA

Apply to skin. Repeat as necessary.

Tube gel with light fragrance.

$0.08/ml

[$9.44]

$9.58/4 oz [114 g, 114.8 mL] tube

Made with Certified Organic Aloe Vera Juice/Gel. No Parabens. No Artificial Colors. No Animal Testing.

Ingredients: Organic Aloe Vera Barbadensis Leaf Juice, Ammonium Polyacryloyl-dimethyl Taurate (Thickener), Benzyl Alcohol (Preservative), Ethylhexyl-glycerin (Preservative), Caprylyl Glycol (Emollient), Organic Aloe Vera Barbadensis Leaf Polysaccharides (Aloesorb™) Retinyl Palmitate (Vitamin A), Tocopheryl Acetate (Vitamin E), Ascorbic Acid (Vitamin C).

Aloe Ferox Capsules (Laxative):

APPROVED

Nature's Way® Aloe Latex With Fennel

Click to View Large Photo

Dist. by Nature's Way Brands, LLC

$ Price Check

1 vegan capsule

140 mg aloe ferox latex
Amount of acemannan not stated

Found:
Acemannan: 1.4 mg
Total Aloins A+B 12.7 mg
Emodin: 81 mcg

Heavy Metals: Pass

Large vegan capsule

Adults and children age 12 years and over: take 1 capsule with a full glass (8 ounces) of liquid at bedtime.

$0.05/vegan capsule

[$0.95]

$5.24/100 vegan capsules

Fennel seed 135 mg per vegan capsule.

Non GMO Project Verified seal. Certified Authentic Tru-ID™ seal. Vegan. Gluten Free. No sugar, salt, yeast, wheat, soy, corn, dairy products, artificial colors, flavors, or preservatives.

Precaution: Not recommended for children under 12. Not for long term use.

1 vegan capsule
Aloe ferox (latex) 140 mg, Fennel (seed) 135 mg.

Other Ingredients: Cellulose, plant-derived capsule (hypromellose), magnesium stearate, silica.

APPROVED

Priority One® Aloe Complex

Click to View Large Photo

Dist. by Priority One Nutritional Supplements, Inc.

1 vegetarian capsule

430 mg Cape Aloe leaf latex, Aloe ferox
100 mg Aloe vera leaf gum 200:1 extract

Expecting 5 mg acemannan

Found:
Acemannan: 4.7 mg

Aloins A+B: 27.4 mg
Emodin: 776 mcg

Heavy Metals: NA

Large vegetarian capsule

Adults take one (1) capsule as needed, or as directed by your physician.

$0.36/vegetarian capsule

[$1.91]

$35.97/100 vegetarian capsules

Non-GMO.

Precaution: For professional use only. Not recommended for children under 12. Not for long-term use.

1 vegetarian capsule
Cape Aloe (leaf latex) (Aloe ferox) 430 mg, Aloe vera (leaf gum) (extract 200:1) 100 mg.

Other Ingredients: Rice chelate, silicon dioxide, gluten free maltodextrin, vegetarian capsule (hypromellose, purified water).

Unless otherwise noted, information about the products listed above is based on the samples purchased by ConsumerLab.com (CL) for this Product Review. Manufacturers may change ingredients and label information at any time, so be sure to check labels carefully when evaluating the products you use or buy. If a product's ingredients differ from what is listed above, it may not necessarily be of the same quality as what was tested.

The information contained in this report is based on the compilation and review of information from product labeling and analytic testing. CL applies what it believes to be the most appropriate testing methods and standards. The information in this report does not reflect the opinion or recommendation of CL, its officers or employees. CL cannot assure the accuracy of information.

Copyright ConsumerLab.com, LLC, 2021 All rights reserved. Not to be reproduced, excerpted, or cited in any fashion without the express written permission of ConsumerLab.com LLC

ConsumerTips™:

Just Gel or Latex as Well?
The first step in choosing an aloe product is deciding whether or not you want aloe latex or just aloe gel.

As noted earlier, latex naturally occurs beneath the skin of the aloe leaf, but can have a significant laxative effect and, based on animal studies, may cause genetic mutations and be carcinogenic (cancer causing) (see Concerns and Cautions). If you don't want the latex (also known as aloins), look for products with just "aloe vera gel," or aloe vera leaf juice that has been processed to remove the latex (look for juice which has been "filtered," "purified," or "decolorized."). You can also look products having the certification seal of the International Aloe Science Council (IASC), which requires certified aloe products for internal consumption to contain less than 10 ppm (parts per million) of aloin. Although not all companies participate in the program, our two Top Picks in this review either had the IASC seal (Lily of the Valley Aloe Vera Juice) or noted that it was made with IASC ingredients (Aubrey Aloe Vera).

If you specifically want aloe latex, perhaps for its laxative effect, look for aloe vera juice which has not been processed (it may be described as "raw") or look for products made from the Aloe ferox species, which has more latex. Two products like these are reviewed above. Keep in mind that a number of other supplements may be safe and helpful for constipation, such as those providing fiber.

Dosage:
For constipation, aloe is typically taken in the evening. The dose is highly dependent on the type of aloe used, but generally ranges from 50 to 200 mg of dried aloe juice (as an extract or powder), or one tablespoon of juice up to three times per day.

For diabetes, one tablespoon of aloe gel daily has been used in clinical studies.

Topical aloe vera cream (containing 0.5% aloe extract) used in clinical studies was applied three times daily to speed healing of herpes lesions.

Quality:
Most aloe products do not list their amounts of acemannan or aloins and ConsumerLab has found that some contain little or no acemannan. Look for a product that has been approved in testing by an independent third-party test, such as ConsumerLab.com or the IASC (see above).

Concerns and Cautions:

Aloe vera "gel" is generally considered safe when taken orally in small doses, although it may lower blood glucose levels. Topically, it may cause an allergic reaction in some people.

Products with aloe vera latex, such as in unpurified aloe vera leaf "juice," may cause diarrhea, which in turn can lead to electrolyte imbalance, kidney dysfunction, dry mouth, headache, and nausea. It should not be used by people with kidney disorders, gastrointestinal disorders, hemorrhoids, or diabetes. These potential negative effects contributed to the FDA's decision to ban the use of aloe in over-the-counter (OTC) drugs (Fed Regist 2002), deeming aloe "not generally safe and effective."

As noted earlier, aloe latex may, according to animal studies, cause genetic mutations and be carcinogenic. The International Agency for Research on Cancer (IARC) of the World Health Organization classifies non-decolorized whole leaf extract of aloe vera as "possibly carcinogenic to humans." Based on the IARC's classification, on December 4, 2015, California's Office of Environmental Health Hazard Assessment (OEHHA) added non-decolorized whole leaf extract of aloe vera to the state's list of chemicals known to cause cancer, as part of its Prop 65 law. The law requires that dietary supplements sold in California include a warning if they contain one or more chemicals on the list, as these substances may cause cancer or reproductive harm. The Prop 65 list does not include aloe vera decolorized whole leaf extract, aloe vera gel, or aloe vera gel extract. Surprisingly, it also does not include aloe vera latex, although it is the latex portion of aloe which has been shown to be a carcinogen.

Women who are pregnant or nursing, children, and the elderly should not use latex-containing aloe products. If aloe vera is used topically on nipples, it should be washed off before nursing as this has been reported to interfere with feeding and cause diarrhea in infants (National Library of Medicine 2020).

People with diabetes should be aware that aloe may potentially cause blood sugar levels to fall too low.

Rarely, liver injury associated with oral consumption of aloe vera extract has been reported. From 2005 to 2016, there have been approximately 12 published reports of cases of liver toxicity (i.e., elevated liver enzymes, jaundice, acute hepatitis) worldwide associated with consuming aloe vera extract, typically occurring between 3 and 24 weeks after starting supplementation. No components of aloe vera extract are known to be particularly toxic to the liver; researchers suspect that certain individuals may be "hypersensitive" or experience an immune system reaction to aloe vera. Most cases resolve when aloe vera extract supplementation is discontinued (LiverTox 2017Yang, J Korean Med Sci 2010).


Information on this site is provided for informational purposes only. It is not an endorsement of any product nor is it meant to substitute for the advice provided by physicians or other healthcare professionals. The information contained herein should not be used for diagnosing or treating a health problem or disease. Consumers should inform their healthcare providers of the dietary supplements they take.

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