Testolone is an unapproved drug that comes with a ton of warnings. Why do people use it? Learn about the risks and dangers of RAD140.<\/p>\n
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Disclaimer<\/i><\/b>:<\/i> While testolone is not illegal to have<\/i><\/b>,<\/i> it is illegal to sell and banned in professional and amateur league sports<\/i><\/b>.<\/i> Some of our readers who were already taking the drug requested that we commission a post on it<\/i><\/b>,<\/i> and we are simply providing information that is available in the clinical and scientific literature<\/i><\/b>.<\/i><\/p>\n
Testolone is an unsafe experimental drug not approved for human consumption<\/i><\/b>.<\/i> Do not take it under any circumstances<\/i><\/b>.<\/i><\/p>\n RAD140, also known as testolone, is a new investigational drug which has become popular among bodybuilders, who claim that it has muscle-building effects. RAD140 belongs to a class of compounds called selective androgen receptor modulators<\/b>, or SARMs<\/b> [R<\/a>].<\/p>\n SARMs bind to androgen receptors that are found in different areas of the body. Normally, these receptors interact with androgens, which are a group of steroid hormones. Androgens like testosterone, dihydrotestosterone, and androstenedione<\/a> are naturally produced by the body [R<\/a>].<\/p>\n SARMs and testosterone tend to have similar effects because they work on the same receptor. The intended targets of SARMs include the muscles, bones, and liver [R<\/a>].<\/p>\n SARMs are of particular interest to researchers because they are selective about where they work. They mostly target muscle and bone tissues<\/b>, and appear to have minimal effects on the prostate and other organs<\/b>. Because of this, some researchers believe that SARMs could potentially treat hormone-related or muscle-wasting disorders with fewer side effects than existing treatments, but this is an unproven hypothesis without data to back it up [R<\/a>].<\/p>\n This potential has also made SARMs a popular choice over testosterone or steroids for bodybuilders. Although testosterone and steroids boost muscle growth, they also have unwanted effects on the prostate and reproductive organs, among others [R<\/a>].<\/p>\n RAD140 has become popular in men with low testosterone levels who want to avoid testosterone replacement therapy but are looking to maintain their physical and sexual performance. Such use is still completely anecdotal, without research to back it up.<\/p>\n In fact, without complete studies, testosterone replacement therapy remains a safer approach than using SARMs like testolone. Remember that we know nothing about the safety profile of this experimental, unapproved drug, while testosterone’s effects are well-studied and predictable.<\/p>\n Research is currently investigating the potential role of RAD140 in increasing muscle mass, fighting breast cancer, and protecting brain cells [R<\/a>, R<\/a>, R<\/a>].<\/p>\n Despite the lack of safety research in humans, bodybuilders use RAD140 to increase strength and endurance. RAD140 is not illegal, but it is banned in professional sports<\/b>. Along with all other SARMs, RAD140 is on the prohibited list of the World Anti-Doping Agency<\/b> [R<\/a>].<\/p>\n RAD140 works by selectively stimulating androgen receptors in the body. It targets receptors in the muscle and bone and has had little to no observed effect on the reproductive organs [R<\/a>].<\/p>\n This compound stimulates muscle growth by promoting the development of muscle cells and proteins [R<\/a>].<\/p>\n The selective ability of SARMs is not fully understood yet. According to some researchers, they may target and selectively activate different proteins than testosterone. This results in only certain androgen receptors – mainly in the muscles – being activated [R<\/a>].<\/p>\n The chemical structure of RAD140 is very different from the structure of steroid hormones like testosterone. Thus, the pathways that convert testosterone into other hormones (like estrogen) cannot act on testolone [R<\/a>].<\/p>\n Based on a study in rats, some researchers have suggested that RAD140 could activate receptors in injured regions of the brain. In the brains of rats given RAD140, MAPK activity increased, thus protecting neurons from damage [R<\/a>].<\/p>\nWhat is RAD140 (Testolone)?<\/span><\/h2>\n
SARMs<\/span><\/h3>\n
Snapshot<\/span><\/h3>\n
Proponents:<\/h4>\n
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Skeptics:<\/h4>\n
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Use in Bodybuilding<\/span><\/h3>\n
Mechanism of Action<\/span><\/h3>\n