{"id":35151,"date":"2019-11-11T12:11:52","date_gmt":"2019-11-11T20:11:52","guid":{"rendered":"https:\/\/selfhacked.com\/?p=35151"},"modified":"2021-11-03T02:12:09","modified_gmt":"2021-11-03T09:12:09","slug":"bromantane","status":"publish","type":"post","link":"https:\/\/selfhacked.com\/blog\/bromantane\/","title":{"rendered":"6 Uses of Bromantane (Ladasten) + Side Effects"},"content":{"rendered":"

Bromantane (Ladasten<\/a>) is a drug that purportedly improves mental and physical performance. It may help relieve fatigue and anxiety<\/a>, improve learning, and help with physical activity. However, there are a few side effects associated with this drug, and there are not many human studies available. Keep reading to learn all about bromantane’s positives and negatives.<\/p>\n

Disclaimer:<\/i><\/b> This post is <\/i>not<\/i> a recommendation or endorsement for the use of bromantane. The FDA has not approved this drug for any specific medical or other use, and the available research on it is still in a very early stage, without adequate data to come to any firm conclusions about its general efficacy or safety in human users. We have written this post for informational purposes only, and our goal is solely to inform people about what science currently says about bromantane\u2019s mechanisms, potential effects, and possible side-effects.<\/i><\/p>\n

What Is Bromantane?<\/b><\/span><\/h2>\n

Bromantane\/bromantan (Ladasten) is a drug developed in Russia in the 1980s. Derived from adamantane, bromantane is an actoprotector<\/b>, which is a kind of drug that enhances physical activity under extreme environmental conditions (such as low oxygen<\/a> or high temperature) [R<\/a>, R<\/a>].<\/p>\n

Bromantane purportedly increases energy, reduces anxiety<\/a>, inhibits fatigue, promotes learning, and improves movement coordination. All of these effects are claimed to combine to help increase both mental and physical performance. In Russia, bromantane is approved for the treatment of neurasthenia [R<\/a>].<\/p>\n

It does not possess any addictive potential and has no serious side effects according to the limited scientific research [R<\/a>].<\/p>\n

However, it is banned from many sports competitions, including the Olympics [R<\/a>].<\/p>\n

Mechanism of Action<\/b><\/span><\/h3>\n

Although bromantane\u2019s exact mechanism is unknown, scientists think that it works by increasing brain activity (in the hippocampus, hypothalamus<\/a> nuclei, and the reticular nuclei of the operculum) [R<\/a>].<\/p>\n

It acts through the dopamine<\/a> system, by increasing tyrosine<\/a> hydroxylase and amino acid decarboxylase. This, in turn, increases dopamine formation<\/b> from tyrosine [R<\/a>, R<\/a>, R<\/a>].<\/p>\n

By increasing dopamine, bromantane may increase alertness and wakefulness [R<\/a>, R<\/a>].<\/p>\n

Bromantane also increases<\/b> serotonin<\/b><\/a> in the brain, which may help increase feelings of happiness [R<\/a>].<\/p>\n

Genetics<\/b><\/span><\/h3>\n

There is no evidence of bromantane\u2019s effects on human genes.<\/p>\n

In rats, bromantane administration to rats increased [R<\/a>]:<\/p>\n