{"id":26741,"date":"2019-12-26T07:09:28","date_gmt":"2019-12-26T15:09:28","guid":{"rendered":"https:\/\/selfhacked.com\/?p=26741"},"modified":"2021-09-20T09:18:18","modified_gmt":"2021-09-20T16:18:18","slug":"l-brevis","status":"publish","type":"post","link":"https:\/\/selfhacked.com\/blog\/l-brevis\/","title":{"rendered":"Could L. brevis Improve Your Health? Immunity, Gut, & More"},"content":{"rendered":"

The probiotic L. brevis<\/em> has many potential benefits to dental health, immunity, and the gut, while new research suggests it could also help with sleep and inflammation. Learn more here.<\/p>\n

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What is Lactobacillus brevis<\/em>?<\/strong><\/span><\/h2>\n

Lactobacillus brevis<\/em> is a plant-derived lactic acid<\/a> bacterium isolated from \u2018Suguki\u2019, a traditional Japanese pickle produced in Kyoto (R<\/a>).<\/p>\n

L. brevis<\/em><\/a> can be found in fermented foods such as sauerkraut and pickles. It is also a normal part of the human gut microbiota<\/a>.<\/p>\n

Health Benefits of L. brevis<\/strong><\/span><\/h2>\n

L. brevis<\/em> probiotic supplements have not been approved by the FDA for medical use and generally lack solid clinical research. Regulations set manufacturing standards for them but don’t guarantee that they’re safe or effective. Speak with your doctor before supplementing.<\/p>\n

Possibly Effective For<\/span><\/h3>\n

1) Immunity<\/h4>\n

L. brevis<\/em> reduced the incidence of influenza in 1089 elementary school children. The improvement was especially pronounced in unvaccinated individuals (R<\/a>).<\/p>\n

Oral administration of live, but not heat-killed, L. brevis<\/em> significantly increased IFN-\u03b1 production in 60 volunteers. The intake tended to be most beneficial in subjects with initially low levels of IFN-\u03b1 production (R<\/a>).<\/p>\n

L. brevis<\/em> alleviated influenza virus infection symptoms in mice (R<\/a>).<\/p>\n

L. brevis<\/em> enhanced cytotoxic activity of mouse splenocytes (R<\/a>).<\/p>\n

L. brevis<\/em> exhibited antiviral activity towards herpes virus (HSV-2) and inhibits HSV-2 multiplication (R<\/a>).<\/p>\n

2) Dental Health<\/h4>\n

L. brevis<\/em> improved oral pH,<\/em> reduced salivary Streptococcus mutans,<\/em> and reduced bleeding on probing in 191 high caries risk schoolchildren (R<\/a>).<\/p>\n

L. brevis<\/em> had anti-inflammatory effects and brought about the total disappearance or amelioration of clinical symptoms in 8 healthy subjects and 21 patients with periodontitis (R<\/a>).<\/p>\n

L. brevis<\/em> exerted oral anti-inflammatory properties, possibly by preventing nitric oxide synthesis, in 34 healthy adults (R<\/a>).<\/p>\n

L. brevis<\/em> inhibited periodontal inflammation, significantly decreased bone loss and lowered the count of anaerobic bacteria in mice with periodontitis (R<\/a>).<\/p>\n

3) Gut Health<\/h4>\n
Constipation<\/h5>\n

Heat-killed L. brevis <\/em>improved intestinal function in 32 women with constipation<\/a> and promoted the growth of Bifidobacteria <\/em>(R<\/a>).<\/p>\n

Marked enhancement of NK-cell activity and improved bowel symptoms were observed in 44 female students with constipation, who consumed pickles containing dead L. brevis<\/em> cells (R<\/a>).<\/p>\n