The gut microbe B. longum may improve the human immune response and help prevent gut disorders. Early evidence suggests that it may also suppress allergies, reduce cholesterol, and improve skin health. Learn more here.<\/p>\n
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Bifidobacterium longum<\/em> is a Gram-positive, rod-shaped species of bacteria naturally present in the human GI tract. It\u2019s subspecies B. longum<\/em> subsp. infantis<\/em> is one of the earliest bacteria to colonize the infant gut. B. longum<\/em> is often added to food products as a probiotic with various health benefits.<\/p>\n Previously considered separate species, B. infantis<\/em><\/a> and B. suis<\/em> were shown to be subspecies of B. longum<\/em> [R<\/a>].<\/p>\n B. longum<\/em> probiotic supplements have not been approved by the FDA for medical use. Supplements generally lack solid clinical research. Regulations set manufacturing standards for them but don’t guarantee that they’re safe or effective. Speak with your doctor before supplementing.<\/p>\n B. longum<\/em> ssp. infantis<\/em> triggered the anti-poliovirus response in a small study of 20 infants [R<\/a>].<\/p>\n B. longum<\/em> ssp. infantis<\/em> promoted the immune response in human volunteers [R<\/a>].<\/p>\n B. longum<\/em> also stimulated immune function in 45 elderly, hospitalized patients who received an influenza vaccine [R<\/a>].<\/p>\n B. longum<\/em> ssp. infantis<\/em> had strong immunomodulatory effect in blood drawn from elderly patients, compared with other well-known commercial strains [R<\/a>].<\/p>\n B. longum <\/em>supplementation reduced the incidence of influenza and fever in 27 elderly subjects who received an influenza vaccine <\/strong>[R<\/a>].<\/p>\n B. longum<\/em> fed infants showed a trend toward fewer respiratory tract infections [R<\/a>].<\/p>\n B. longum<\/em> protected mice against pneumonia-induced death by finely tuning the inflammatory response and speeding up lung recovery [R<\/a>].<\/p>\n B. longum<\/em> improved symptoms, reduces mortality and suppresses inflammation in the lower respiratory tract in mice infected with influenza [R<\/a>, R<\/a>].<\/p>\n B. longum<\/em> ssp. infantis<\/em> inhibited rotavirus infection in mice [R<\/a>].<\/p>\n Oral administration of B. longum<\/em> protects mice against gut-derived sepsis caused by P. aeruginosa<\/em> [R<\/a>].<\/p>\n B. longum<\/em> improves survival in mice infected with Salmonella<\/em> Typhimurium [R<\/a>].<\/p>\n B. longum<\/em> ssp. infantis<\/em> protects against Salmonella associated injury in mice via a Treg<\/a>-dependent mechanism [R<\/a>, R<\/a>].<\/p>\n B. longum<\/em> inhibits the growth of C. albicans<\/em> and other pathogenic bacteria [R<\/a>].<\/p>\n B. longum<\/em> ssp. infantis<\/em> reduced gastrointestinal symptoms in untreated Celiac disease<\/strong> (CD) patients [R<\/a>].<\/p>\n B. longum<\/em> improved<\/strong> gut microbiota<\/strong><\/a> composition and immune parameters<\/strong> in children with newly diagnosed CD [R<\/a>].<\/p>\n Oral administration of B. longum<\/em> ameliorated gliadin (gluten)-mediated perturbations in liver iron<\/a> deposition and mobilization in rats with CD [R<\/a>].<\/p>\n B. longum<\/em> attenuated the production of inflammatory cytokines and the CD4+ T-cell mediated immune response and protects newborn rats against gliadin (gluten)-induced enteropathy [R<\/a>].<\/p>\n<\/a>Potential Benefits of B. longum<\/em><\/strong><\/span><\/h2>\n
<\/a>Possibly Effective<\/span><\/h3>\n
<\/a>1) Immunity<\/h4>\n
<\/a>Infections<\/h5>\n
<\/a>Candida<\/em> Infection<\/h5>\n
<\/a>2) Celiac Disease<\/h4>\n