{"id":21691,"date":"2019-12-28T14:04:03","date_gmt":"2019-12-28T22:04:03","guid":{"rendered":"https:\/\/selfhacked.com\/?p=21691"},"modified":"2021-09-20T09:17:42","modified_gmt":"2021-09-20T16:17:42","slug":"vanilla","status":"publish","type":"post","link":"https:\/\/selfhacked.com\/blog\/vanilla\/","title":{"rendered":"Vanilla: Potential Uses, Health Effects, and Safety"},"content":{"rendered":"<p>Vanilla is a great spice with versatile uses in cooking and cosmetics. This post reveals less-known potential uses and health effects of vanilla, along with safety precautions.<\/p>\n<p><!--more--><\/p>\n<h2><span id=\"What_is_Vanilla\"><strong>What is Vanilla?<\/strong><\/span><\/h2>\n<p>Vanilla is an extract from the vanilla bean. It has many culinary and cosmetic uses. However, vanilla and its flavoring extracts also have potential health effects worth further research. For example, the extract vanillin has been studied for its potential role in the management of sickle cell anemia.<\/p>\n<h3><span id=\"Antimicrobial_Properties\"><strong>Antimicrobial Properties<\/strong><\/span><\/h3>\n<p>Vanillin shows antimicrobial properties against E Coli and Listeria [<a href=\"https:\/\/www.researchgate.net\/publication\/8521550_Mode_of_antimicrobial_action_of_vanillin_against_Escherichia_coli_Lactobacillus_plantarum_and_Listeria_innocua_J_Appl_Microbiol\">R<\/a>].<\/p>\n<p><a href=\"https:\/\/selfhacked.com\/blog\/44-science-backed-ways-to-inhibit-biofilms-naturally-with-references\/\">Biofilms<\/a> are microbial films that are embedded in a self-produced matrix [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25189863\">R<\/a>].<\/p>\n<p><a href=\"http:\/\/selfhacked.com\/blog\/all-about-quorum-sensing-and-natural-quorum-sensing-inhibitors\/\">Quorum sensing<\/a> is a process by which bacteria produce and detect signal molecules and thereby coordinate their behavior. Vanilla is a unique quorum sensing inhibitor and this may help break up biofilms [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25189863\">R<\/a>].<\/p>\n<h3><span id=\"Antioxidant_Properties\"><strong>Antioxidant Properties<\/strong><\/span><\/h3>\n<p>Extracts of vanilla pods scavenged radicals in a concentration-dependent manner [<a href=\"http:\/\/www.ijsrp.org\/research-paper-1113\/ijsrp-p2356.pdf\">R<\/a>].<\/p>\n<p>Various extracts scavenged hydroxyl and nitric oxide radicals [<a href=\"http:\/\/www.ijsrp.org\/research-paper-1113\/ijsrp-p2356.pdf\">R<\/a>].<\/p>\n<p>Treatment with vanillin ameliorated impaired mitochondrial enzyme complexes (I, II, and IV) in the animal model of Huntington\u2019s disease. Further, it could inhibit singlet oxygen-induced protein and lipid oxidation [<a href=\"http:\/\/www.hindawi.com\/journals\/ecam\/2015\/626028\/\">R<\/a>].<\/p>\n<p>The effect on oxidation is similar to <a href=\"http:\/\/selfhacked.com\/blog\/need-know-vitamin-c-32-science-based-health-benefits\/\">Vitamin C<\/a> but less effective than <a href=\"http:\/\/selfhacked.com\/blog\/30-scientifically-proven-health-benefits-glutathione\/\">glutathione<\/a> [<a href=\"http:\/\/link.springer.com\/article\/10.1023\/A:1007048313556\">R<\/a>].<\/p>\n<p>Vanilla inhibited the oxidation of <a href=\"https:\/\/selfhacked.com\/blog\/ldl-cholesterol\/\">LDL<\/a> cholesterol in rats [<a href=\"http:\/\/nopr.niscair.res.in\/bitstream\/123456789\/16551\/1\/IJEB%2051(4)%20288-291.pdf\">R<\/a>].<\/p>\n<h2><span id=\"Other\"><strong>Other<\/strong><\/span><\/h2>\n<p>Vanillin shows dose-dependent inhibition of deoxygenation-induced cell sickling, which might help for sickle cell anemia [<a href=\"http:\/\/www.bloodjournal.org\/content\/77\/6\/1334.short?sso-checked=true\">R<\/a>].<\/p>\n<p>Oral vanillin decreased the percentage of sickled red blood cells in 30 patients with sickle-cell anemia [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16114181\">R<\/a>].<\/p>\n<p><strong>Until more research is done, we can\u2019t make any conclusions about the therapeutic potential of vanillin in sickle-cell anemia. Additionally, vanilla extract likely wouldn\u2019t produce the same effects.<\/strong><\/p>\n<h2><span id=\"Side_Effects_and_Risks\"><strong>Side Effects and Risks<\/strong><\/span><\/h2>\n<p>Vanilla is generally safe and well-tolerated in the amounts usually present in food. Vanillin at extreme doses may have some carcinogenic effects. An animal study on vanillin safety concludes [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3523249\/\">R<\/a>]:<\/p>\n<p>&#8220;Vanillin was not cocarcinogenic when consumed orally. However, it was cocarcinogenic when being administered intraperitoneally at high concentrations. Hence, the use of vanillin in food should be safe but might have cocarcinogenic potential when it is used in high concentration for therapeutic purposes.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vanilla is a great spice with versatile uses in cooking and cosmetics. This post reveals less-known potential uses and health effects of vanilla, along with safety precautions.<\/p>\n","protected":false},"author":15399,"featured_media":67305,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[347,22],"tags":[279,292],"yst_prominent_words":[8860,11198,4786,2279,6218,14969,730,560,6769,16804,6221,15897,3538,6216,6219,6214,32657,17381,6215,6217],"_links":{"self":[{"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/posts\/21691"}],"collection":[{"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/users\/15399"}],"replies":[{"embeddable":true,"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/comments?post=21691"}],"version-history":[{"count":15,"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/posts\/21691\/revisions"}],"predecessor-version":[{"id":115967,"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/posts\/21691\/revisions\/115967"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/media\/67305"}],"wp:attachment":[{"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/media?parent=21691"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/categories?post=21691"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/tags?post=21691"},{"taxonomy":"yst_prominent_words","embeddable":true,"href":"https:\/\/selfhacked.com\/wp-json\/wp\/v2\/yst_prominent_words?post=21691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}