Comments on: Noopept: Purported Uses, Side-Effects, and Risks

By: Bill Doolittle

Bill Doolittle — Fri, 28 Jun 2019 11:43:31 +0000

Would like to understand how Noopept might benefit those suffering with Parkinson’s Disease.

By: Thomas

Thomas — Wed, 03 Jan 2018 10:19:32 +0000

Above is stated:
Its primary mechanism of action is increasing the activity of HIF1A, a DNA transcription factor [R].

From wikipedia:
HIF-1 is overexpressed in many human cancers.[50][51] HIF-1 overexpression is heavily implicated in promoting tumor growth and metastasis through its role in initiating angiogenesis and regulating cellular metabolism to overcome hypoxia.[52] Hypoxia promotes apoptosis in both normal and tumor cells.[53] However, hypoxic conditions in tumor microenvironment especially, along with accumulation of genetic alternations often contribute to HIF-1 overexpression.[10].

Is this relevant? Or is HIF1A only increased in brain?

By: Shawn Elmer

Shawn Elmer — Thu, 05 Oct 2017 21:16:47 +0000

Note to the author: BDNF is the abbreviation for BRAIN DERIVED NOOTROPHIC FACTOR not brain derived nerve growrh factor. As far as stacks, The supplemt “Focus factor” is a wonderful supp to take with noopept. It is a synergy of many of the main precursors of brain neurotransmitters, trace minerals, substances that inhibit the break down of ach as well as omegas and herbs that greatly increase brain blood flow, oxegen uptake in the brain and other anti oxidants.
Shawn

By: Markus

Markus — Mon, 22 May 2017 17:21:58 +0000

Short note: It tends to be absorbed best when taken sublingually for 30-60+ seconds.

Since it’s practically just 2 amino acids attached, stomach acid tends to cleave most of it into those 2 AAs…making you need to take much more to feel the desired effects.