Comments on: What is Leptin? Definition, Function & Normal Levels https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/ Cutting-Edge Solutions For a Better Life Thu, 17 Sep 2020 08:15:05 +0000 hourly 1 https://wordpress.org/?v=5.8.1 By: Ana Aleksic, MSc (Pharmacy) https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-45498 Tue, 30 Apr 2019 14:49:32 +0000 https://selfhacked.com/?p=15343#comment-45498 In reply to Abdul.

Thanks, Abdul!

]]> By: Abdul https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-45352 Sun, 28 Apr 2019 12:57:59 +0000 https://selfhacked.com/?p=15343#comment-45352 Since I stumbled on your site, I’ve been learning a whole lot. Nice Job.

]]> By: Grey Ghost https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-31974 Thu, 05 Apr 2018 15:21:37 +0000 https://selfhacked.com/?p=15343#comment-31974 I also am looking to better understand how I can lose weight (fat), while having leptin intolerance due to CIRS. A ketogenic diet has been somewhat helpful, but it has been difficult to even lose 5 lbs, while my healthy male partner has dropped 20+ with almost no effort. It is really frustrating to have such a limited diet and see minimal results, but if I do start eating carbs again, I gain weight back very quickly and it is very slow to lose again. Will I have to be on a ketogenic diet forever? If so, I’d at least love it to be effective for weight loss.

]]> By: Claudia Rowe https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-21760 Thu, 22 Jun 2017 06:17:48 +0000 https://selfhacked.com/?p=15343#comment-21760 I’d love to know the answer to that question. I’ve had chronically high leptin serum levels since 2007 (+50) with no lifestyle factors at all – eat flesh and veges, low fat, good fat, exercise regularly. No endo seems to able to explain why. Some seem to think it’s irrelevant and I should just try “harder” to diet.

]]> By: Nattha Wannissorn, PhD https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-21618 Fri, 16 Jun 2017 16:11:25 +0000 https://selfhacked.com/?p=15343#comment-21618 In reply to Kathy Clester.

https://selfhacked.com/blog/balance-elevated-th1-th2-immune-system/
Focus on Treg and lowering Th17.
Then sleep well, eat well, reduce stress etc are no brainers.

]]> By: Kathy Clester https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-21617 Fri, 16 Jun 2017 16:07:50 +0000 https://selfhacked.com/?p=15343#comment-21617 What if your th1 and th2 dominant? I got into both categories. Over active and under active immune system. Severe allergies, hit, all sorts homozygous genes. I need to balance everything. How does one do that? High tnf alpha, tried enbrel that shot my histamine through the roof. Antihistamines make me worse by just blocking histamine and not breaking it down. Where does one start?

]]> By: Nattha Wannissorn https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-19204 Tue, 03 Jan 2017 21:22:49 +0000 https://selfhacked.com/?p=15343#comment-19204 In reply to Ruthus Keller.

It depends on the context. Elevated leptin is like in very obese individuals. However, healthy levels of leptin and leptin sensitivity are good.

]]> By: Ruthus Keller https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-19202 Tue, 03 Jan 2017 20:41:39 +0000 https://selfhacked.com/?p=15343#comment-19202 How does can Leptin do one thing and at the same time the opposite.
You’ve written elevated Leptin is pro inflammatory, but if you give Leptin to mice there has been shown reduced anxiety and depression, when we know that depression is caused by inflammation in glands in the brain, among other things. Crazy. For me this article is confuse. Revise it, please.

]]> By: Van Beran https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-18042 Tue, 23 Aug 2016 14:40:32 +0000 https://selfhacked.com/?p=15343#comment-18042 I have gained weight as of late. Daniel said I won’t be able to lose weight due to high Leptin in my blood. Ugh! It’s been quite frustrating. I also see where this can lead to an increase in Melanoma. And I have had countless “bad moles” removed wide excision this year. How can I, in layman English, lower Leptin? (Thank you in advance)

]]> By: Dot SLady https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-16848 Sat, 26 Mar 2016 13:55:38 +0000 https://selfhacked.com/?p=15343#comment-16848 How would pyroluria be involved with leptin resistance? http://bit.ly/1UzkImX

]]> By: Joseph M. Cohen https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-16815 Fri, 25 Mar 2016 00:16:52 +0000 https://selfhacked.com/?p=15343#comment-16815 In reply to James.

Could be lower leptin, lower VIP, higher NAD+, lower T3, a combination or other.

]]> By: James https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-16803 Wed, 23 Mar 2016 22:02:49 +0000 https://selfhacked.com/?p=15343#comment-16803 Interesting, I have chronic achilles tendinopathy and the pain went away when I fasted. Could there be a leptin connection. I thought it might be ketones making the pain go.

]]> By: Jason Coates https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-16795 Wed, 23 Mar 2016 07:29:29 +0000 https://selfhacked.com/?p=15343#comment-16795 Good one Joe!

]]> By: Jude from Australia https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-16794 Wed, 23 Mar 2016 06:26:44 +0000 https://selfhacked.com/?p=15343#comment-16794 So tell me – have you figured out how to lose weight when you’re leptin resistant??

]]> By: Joseph M. Cohen https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-16793 Wed, 23 Mar 2016 04:49:06 +0000 https://selfhacked.com/?p=15343#comment-16793 In reply to anna burns.

How to increase Th2 dominance

]]> By: anna burns https://selfhacked.com/blog/all-about-leptin-its-role-in-chronic-inflammation-cfs-and-weight/#comment-16790 Wed, 23 Mar 2016 02:14:05 +0000 https://selfhacked.com/?p=15343#comment-16790 you said that leptin increases th-1 dominance. I wonder, what would increase th-2 dominance?

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